Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Phenbenzamine hydrochloride
RN: 2045-52-5
UNII: U213O3K2JW
InChIKey: AJCNOWKYMZKMFV-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H22-N2.Cl-H

Molecular Weight

  • 290.836
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Phenbenzamine hydrochloride

Name of Substance

  • Phenbenzamine hydrochloride

Synonyms

  • 2339 R.P. hydrochloride
  • Aniline, N-benzyl-N-dimethylaminoethyl-, hydrochloride
  • Antergan hydrochloride
  • CCRIS 4856
  • Compound 2339 RP
  • Corps 2339 R P
  • Corps 2339 R P [French]
  • N-Dimethylaminoethylbenzylaniline hydrochloride
  • N-Phenyl-N-benzyl-N',N'-dimethylethylenediamine hydrochloride
  • NSC 59803
  • Phenbenzamine chloride
  • Phenbenzamine hydrochloride
  • UNII-U213O3K2JW

Systematic Names

  • 1,2-Ethanediamine, N,N-dimethyl-N'-phenyl-N'-(phenylmethyl)-, monohydrochloride
  • 1,2-Ethanediamine, N,N-dimethyl-N'-phenyl-N'-(phenylmethyl)-, monohydrochloride (9CI)
  • Ethylenediamine, N-benzyl-N',N'-dimethyl-N-phenyl-, hydrochloride
  • Phenbenzamine hydrochloride

Registry Numbers

CAS Registry Number

  • 2045-52-5

FDA UNII

  • U213O3K2JW

System Generated Number

  • 0002045525

Molecular Formulas

Molecular Formula

  • C17-H22-N2.Cl-H

Molecular Formula Fragments

  • C17-H22-N2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H22N2.ClH/c1-18(2)13-14-19(17-11-7-4-8-12-17)15-16-9-5-3-6-10-16;/h3-12H,13-15H2,1-2H3;1H

InChIKey

AJCNOWKYMZKMFV-UHFFFAOYSA-N

Smiles

N(c1ccccc1)(Cc1ccccc1)CC[NH+](C)C.[ClH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 subcutaneous 110mg/kg (110mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Physiological Reviews. Vol. 27, Pg. 542, 1947.
mouse LD50 intravenous 35mg/kg (35mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 210, 1948.
mouse LD50 oral 325mg/kg (325mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 210, 1948.
mouse LD50 subcutaneous 125mg/kg (125mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 210, 1948.
rabbit LD50 intravenous 15mg/kg (15mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 210, 1948.
rat LD50 oral 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 68, Pg. 339, 1942.
rat LDLo subcutaneous 15mg/kg (15mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 144, Pg. 887, 1950.