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Substance Name: Cetuximab [USAN:INN]
RN: 205923-56-4
UNII: PQX0D8J21J

Note

  • A chimeric monoclonal antibody that functions as an ANTINEOPLASTIC AGENT through its binding to the EPIDERMAL GROWTH FACTOR RECEPTOR, where it prevents the binding and signaling action of cell growth and survival factors.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Antineoplastic Agents
  • Monoclonal Antibody
  • Treatment of EGF Receptor-Expressing Cancers (Monoclonal Antibody)

Names and Synonyms

Name of Substance

  • Cetuximab
  • Cetuximab [USAN:INN]

MeSH Heading

  • Cetuximab

Synonyms

  • C225
  • Cetuximab
  • Erbitux
  • HSDB 7454
  • IMC-C225
  • Immunoglobulin G1 (human-mouse monoclonal C225 gamma1-chain anti-human epidermal growth factor receptor), disulfide with human-mouse monoclonal C225 K-chain, dimer. Molecular weight is approximately 170,000 daltons
  • UNII-PQX0D8J21J

Systematic Name

  • Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-mouse monoclonal C225 gamma1-chain), disulfide with human-mouse monoclonal C225 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 205923-56-4

FDA UNII

  • PQX0D8J21J

System Generated Number

  • 0205923564