Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Bamifylline hydrochloride [USAN]
RN: 20684-06-4
UNII: 66466QLM3S
InChIKey: PDBXHPORMXSXKO-UHFFFAOYSA-N

Classification Codes

  • Bronchodilator
  • Drug / Therapeutic Agent

Molecular Formula

  • C20-H27-N5-O3.Cl-H

Molecular Weight

  • 421.9262
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Bamifylline hydrochloride [USAN]

Synonyms

  • 7-(N-(beta-Hydroxyethyl)-N-ethyl)-aminoethyl-8-benzyl-theophylline hydrochloride
  • 8'-Benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)theophylline hydrochloride
  • 8-Benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)theophylline monohydrochloride
  • 8-Benzyl-7-(N-ethyl-N-(beta-hydroxyethyl)aminoethyl)theophylline hydrochloride
  • 8102 CB
  • AC 3810
  • Bamifylline HCl
  • Bamifylline hydrochloride
  • Bamiphylline hydrochloride
  • BAX 2739Z
  • BAX 2793Z
  • Benzetamophylline hydrochloride
  • Briofil
  • CB 8102
  • EINECS 243-967-6
  • Pulmac
  • Trentadil
  • UNII-66466QLM3S

Systematic Names

  • 1H-Purine-2,6-dione, 7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)-3,7-dihydro-1,3-dimethyl-8-(phenylmethyl)-, monohydrochloride
  • Bamifylline hydrochloride
  • Theophylline, 8-benzyl-7-(2-(ethyl(2-hydroxyethyl)amino)ethyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 20684-06-4

FDA UNII

  • 66466QLM3S

Related Registry Number

  • 2016-63-9 (Parent)

System Generated Number

  • 0020684064

Molecular Formulas

Molecular Formula

  • C20-H27-N5-O3.Cl-H

Molecular Formula Fragments

  • C20-H27-N5-O3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C20H27N5O3.ClH/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2;/h5-9,26H,4,10-14H2,1-3H3;1H

InChIKey

PDBXHPORMXSXKO-UHFFFAOYSA-N

Smiles

CCN(CCn1c(nc2c1c(=O)n(c(=O)n2C)C)Cc3ccccc3)CCO.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 28800ug/kg (28.8mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
dog LD50 oral 614mg/kg (614mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
guinea pig LD50 oral 165mg/kg (165mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
mouse LD50 intraperitoneal 89400ug/kg (89.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
mouse LD50 intravenous 66800ug/kg (66.8mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
mouse LD50 oral 246mg/kg (246mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
rat LD50 intraperitoneal 131mg/kg (131mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
rat LD50 intravenous 64800ug/kg (64.8mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.
rat LD50 oral 1139mg/kg (1139mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 460, 1968.