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Substance Name: Bromofos [INN]
RN: 2104-96-3
UNII: 74A4TNE8C3
InChIKey: NYQDCVLCJXRDSK-UHFFFAOYSA-N

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Human Data
  • Insecticide
  • Mutation Data
  • Reproductive Effect

Molecular Formula

  • C8-H8-Br-Cl2-O3-P-S

Molecular Weight

  • 365.9982
 
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Names and Synonyms

Name of Substance

  • Bromofos [INN]
  • Bromophos
  • Bromophos [BSI:ISO]

Synonyms

  • 4-Bromo-2,5-dichlorophenyl dimethyl phosphorothionate
  • AI3-27162
  • BRN 1988276
  • Brofene
  • Bromo-phos-methyl
  • Bromofos
  • Bromofos-methyl
  • Bromofosum
  • Bromofosum [INN-Latin]
  • Bromophos
  • Bromovur
  • Brophene
  • Bruomophos
  • Bruomophos [Russian]
  • Caswell No. 114E
  • Cela S 1942
  • Cx99
  • Drillzid
  • EINECS 218-277-3
  • EL 400
  • ENT 27,162
  • EPA Pesticide Chemical Code 008706
  • HSDB 6573
  • Metabrom
  • Mexion
  • Monsanto CP 51969
  • Netal
  • Nexagan
  • Nexion
  • Nexion 40
  • Nexion 5G
  • Nexion LC40
  • NSC 527602
  • O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) phosphorothioate
  • O,O-Dimethyl O-(2,5-dichloro-4-bromophenyl) thiophosphate
  • O,O-Dimethyl O-(4-bromo-2,5-dichlorophenyl) phosphorothioate
  • O,O-Dimethyl-O-(2,5-dichlor-4-bromphenyl)-thionophosphat
  • O,O-Dimethyl-O-(2,5-dichlor-4-bromphenyl)-thionophosphat [German]
  • O,O-Dimethyl-O-(2,5-dichloro-4-bromophenyl)phosphorothioate
  • O,O-Dimethyl-O-2,5-dichloro-4-bromophenyl phosphorothionate
  • O-(4-Brom-2,5-dichlor-phenyl)-O,O-dimethyl-monothiophosphat
  • O-(4-Brom-2,5-dichlor-phenyl)-O,O-dimethyl-monothiophosphat [German]
  • O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl monothiophosphate
  • O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl phosphorothioate
  • O-(4-Bromo-2,5-dicloro-fenil)-O,O-dimetil-monotiofosfato
  • O-(4-Bromo-2,5-dicloro-fenil)-O,O-dimetil-monotiofosfato [Italian]
  • O-(4-Broom-2,5-dichloor-fenyl)-O,O-dimethyl-monothiofosfaat
  • O-(4-Broom-2,5-dichloor-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch]
  • Omexan
  • OMS 658
  • OMS-658
  • Phenol, 4-bromo-2,5-dichloro-, O-ester with O,O-dimethyl phosphorothioate
  • Phosphorothioic acid O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester
  • S 1942
  • S-1942
  • Sovinexion
  • Thiophosphate de O,O-dimethyle et de O-4-bromo-2,5-dichlorophenyle
  • Thiophosphate de O,O-dimethyle et de O-4-bromo-2,5-dichlorophenyle [French]
  • UNII-74A4TNE8C3

Systematic Names

  • Bromophos
  • O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl phosphorothioate
  • Phosphorothioic acid, O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester

Registry Numbers

CAS Registry Number

  • 2104-96-3

FDA UNII

  • 74A4TNE8C3

Other Registry Numbers

  • 12778-41-5
  • 12778-42-6

System Generated Number

  • 0002104963

Structure Descriptors

InChI

1S/C8H8BrCl2O3PS/c1-12-15(16,13-2)14-8-4-6(10)5(9)3-7(8)11/h3-4H,1-2H3

InChIKey

NYQDCVLCJXRDSK-UHFFFAOYSA-N

Smiles

COP(=S)(OC)Oc1cc(c(cc1Cl)Br)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 750mg/kg (750mg/kg)   Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
chicken LD50 oral 9700mg/kg (9700mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
guinea pig LD50 oral 1500mg/kg (1500mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

BEHAVIORAL: MUSCLE WEAKNESS
Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
mammal (species unspecified) LD50 skin 2820mg/kg (2820mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(7), Pg. 34, 1977.
mammal (species unspecified) LD50 unreported 3750mg/kg (3750mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(8), Pg. 82, 1976.
mouse LD50 intraperitoneal 1040mg/kg (1040mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
mouse LD50 oral 2829mg/kg (2829mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rabbit LD50 oral 720mg/kg (720mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rabbit LD50 skin 2181mg/kg (2181mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rat LD50 intraperitoneal 1625mg/kg (1625mg/kg)   Defense des Vegetaux. Vol. 32, Pg. 40, 1978.
rat LD50 oral 1600mg/kg (1600mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 skin > 5gm/kg (5000mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 subcutaneous > 12gm/kg (12000mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Azabu Juika Daigaku Kenkyu Hokoku. Bulletin of Azabu Veterinary College. Vol. 30, Pg. 213, 1975.
women TDLo oral 152mg/kg (152mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE
Journal of Toxicology, Clinical Toxicology. Vol. 29, Pg. 203, 1991.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 53.5 deg C   EXP
log P (octanol-water) 5.21 (none)   EXP
Water Solubility 0.3 mg/L 20 EXP
Vapor Pressure 1.28E-04 mm Hg 20 EXP
Henry's Law Constant 2.05E-04 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 5.90E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.