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Substance Name: Laronidase [USAN:INN]
RN: 210589-09-6
UNII: WP58SVM6R4

Note

  • An enzyme that hydrolyzes iduronosidic linkages in desulfated dermatan. Deficiency of this enzyme produces Hurler's syndrome. EC 3.2.1.76.

Molecular Formula

  • C3567-H5645-N921-O1261
 

Classification Code

  • Enzyme Replacement in Mucopolysaccharidosis I (MPS I)

Names and Synonyms

Name of Substance

  • Laronidase
  • Laronidase [USAN:INN]

MeSH Heading

  • Iduronidase

Synonyms

  • Aldurazyme
  • alpha-L-Idosiduronase
  • EC 3.2.1.76
  • Iduronidase, alpha-L-(8-histidine) (human). Molecular weight is approximately 82,000 daltons
  • Laronidase
  • Laronidase (genetical recombination)
  • UNII-WP58SVM6R4

Systematic Names

  • alpha-L-Iduronidase
  • Human Recombinant alpha-L-iduronidase
  • Iduronidase, alpha-L-(8-histidine) (human)

Registry Numbers

CAS Registry Number

  • 210589-09-6

FDA UNII

  • WP58SVM6R4

System Generated Number

  • 0210589096