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Substance Name: Dabigatran [USAN:INN:BAN]
RN: 211914-51-1
UNII: I0VM4M70GC
InChIKey: YBSJFWOBGCMAKL-UHFFFAOYSA-N

Note

  • A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

Molecular Formula

  • C25-H25-N7-O3

Molecular Weight

  • 471.5185
 

Classification Codes

  • Anticoagulants
  • Antithrombins
  • Deep Vein Thrombosis After Surgery, Venous Thromboembolic Events, Stroke Prevention in Atrial Fibrillation
  • Enzyme Inhibitors
  • Hematologic Agents
  • Protease Inhibitors
  • Serine Proteinase Inhibitors
  • Thrombin Inhibitor

Names and Synonyms

Name of Substance

  • Dabigatran [USAN:INN:BAN]

MeSH Heading

  • Dabigatran

Synonyms

  • 3-(((2-(((4-Carbamimidoylphenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)(pyridin-2-yl)amino)propanoic acid
  • beta-Alanine, N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-
  • BIBR 953
  • BIBR 953 ZW
  • Dabigatran
  • HSDB 8062
  • N-((2-((p-Amidinoanilino)methyl)-1-methyl-5-benzimidazolyl)carbonyl)-N-2-pyridyl-beta-alanine
  • Pradaxa
  • UNII-I0VM4M70GC

Systematic Name

  • N-((2-((p-Amidinoanilino)methyl)-1-methyl-5-benzimidazolyl)carbonyl)-N-2-pyridyl-beta-alanine

Registry Numbers

CAS Registry Number

  • 211914-51-1

FDA UNII

  • I0VM4M70GC

System Generated Number

  • 0211914511

Structure Descriptors

InChI

1S/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)

InChIKey

YBSJFWOBGCMAKL-UHFFFAOYSA-N

Smiles

c1cc(cc2c1n(c(n2)CNc1ccc(cc1)C(=N)N)C)C(=O)N(CCC(=O)O)c1ncccc1