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Substance Name: Fludarabine [INN]
RN: 21679-14-1
UNII: P2K93U8740
InChIKey: HBUBKKRHXORPQB-FJFJXFQQSA-N
Classification Codes
- Antineoplastic Agents
- Mutation Data
Molecular Formula
- C10-H12-F-N5-O4
Molecular Weight
- 285.2338
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Fludarabine
- Fludarabine [INN]
Synonyms
- 2-Fluoro Ara-A
- 2-Fluoro-9-beta-D-arabinofuranosyladenine
- 9-beta-D-Arabinofuranosyl-2-fluoroadenine
- CCRIS 3382
- EINECS 244-525-5
- F-Ara-A
- Fludarabina
- Fludarabina [Spanish]
- Fludarabine
- Fludarabinum
- Fludarabinum [Latin]
- HSDB 6964
- NSC 118218
- NSC 118218H
- UNII-P2K93U8740
Systematic Names
- 9-beta-D-Arabinofuranosyl-2-fluoroadenine
- 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro- (9CI)
- Adenine, 9-beta-D-arabinofuranosyl-2-fluoro-
- Fludarabine
Registry Numbers
CAS Registry Number
- 21679-14-1
FDA UNII
- P2K93U8740
System Generated Number
- 0021679141
Structure Descriptors
InChI
InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1InChIKey
HBUBKKRHXORPQB-FJFJXFQQSA-NSmiles
Nc1nc(F)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 375mg/kg (375mg/kg) | Cancer Research. Vol. 42, Pg. 2587, 1982. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 260 | deg C | EXP | |
| log P (octanol-water) | -1.180 | (none) | EST | |
| Water Solubility | 3530 | mg/L | 25 | EST |
| Vapor Pressure | 3.70E-15 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.30E-22 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 2.38E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.