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Substance Name: Pegvisomant [USAN:INN:BAN]
RN: 218620-50-9
UNII: N824AOU5XV

Note

  • Is a genetically engineered analogue of human growth hormone that functions as a growth hormone-receptor antagonist; used to treat Acromegaly.

Molecular Formula

  • Unspecified
 

Classification Code

  • Treatment of Acromegaly (Competitive Inhibition of Peripheral Growth Hormone Receptors to Block IFG-I Production)

Names and Synonyms

Name of Substance

  • Pegvisomant
  • Pegvisomant [USAN:INN:BAN]

Synonyms

  • B 2036
  • B 2036PEG
  • B2036
  • B2036-PEG
  • PEG-hGHra
  • Pegvisomant
  • PNU 467MET0435
  • Somavert
  • Trovert
  • UNII-N824AOU5XV

Systematic Names

  • Somatotropin (18-aspartic acid, 21-asparagine, 120-lysine, 167-asparagine, 168-alanine, 171-serine, 172-arginine, 174-serine, 179-threonine)(human), pegylated
  • Somatotropin (18-aspartic acid, 21-asparagine, 120-lysine, 167-asparagine,168-alanine, 171-serine, 172-arginine, 174-serine, 179-threonine) (human), pegylated 191

Registry Numbers

CAS Registry Number

  • 218620-50-9

FDA UNII

  • N824AOU5XV

Other Registry Number

  • 236101-82-9

System Generated Number

  • 0218620509