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Substance Name: Naepaine
RN: 2188-67-2
UNII: J1Z219971C
InChIKey: UYXHCVFXDBNRQW-UHFFFAOYSA-N

Molecular Formula

  • C14-H22-N2-O2

Molecular Weight

  • 250.34
 
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Names and Synonyms

Name of Substance

  • Naepaine

Synonyms

  • 2-(Pentylamino)ethanol 4-aminobenzoate (ester)
  • 2-n-Amylaminoethyl p-aminobenzoate
  • 2-n-Pentylaminoethyl p-aminobenzoate
  • 3-14-00-01040 (Beilstein Handbook Reference)
  • Amalcaine
  • Amylcain
  • Amylcaine
  • Amylsin
  • Amylsine
  • Benzoic acid, p-amino-, 2-(pentylamino)ethyl ester
  • BRN 2808234
  • Naepaine
  • Naopaine
  • NSC 41534
  • p-Aminobenzoic acid 2-n-amylaminoethyl ester
  • p-Aminobenzoic acid 2-n-pentylaminoethyl ester
  • UNII-J1Z219971C

Systematic Names

  • Benzoic acid, p-amino-, 2-(pentylamino)ethyl ester
  • Ethanol, 2-(pentylamino)-, 4-aminobenzoate (ester) (9CI)
  • Ethanol, 2-(pentylamino)-, p-aminobenzoate (ester) (8CI)

Registry Numbers

CAS Registry Number

  • 2188-67-2

FDA UNII

  • J1Z219971C

System Generated Number

  • 0002188672

Structure Descriptors

InChI

1S/C14H22N2O2/c1-2-3-4-9-16-10-11-18-14(17)12-5-7-13(15)8-6-12/h5-8,16H,2-4,9-11,15H2,1H3

InChIKey

UYXHCVFXDBNRQW-UHFFFAOYSA-N

Smiles

c1(C(OCCNCCCCC)=O)ccc(N)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938.
mouse LDLo subcutaneous 350mg/kg (350mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938.
rabbit LDLo intravenous 18mg/kg (18mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938.