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Substance Name: Lycorine hydrochloride
RN: 2188-68-3
UNII: 58F70VH0HS
InChIKey: VUVNTYCHKZBOMV-NVJKKXITSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C16-H17-N-O4.Cl-H

Molecular Weight

  • 323.774
 
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Names and Synonyms

Results Name

  • Lycorine hydrochloride

Name of Substance

  • Lycorine hydrochloride

Synonyms

  • Galanthan-1,2-diol, 3-12-didehydro-9,10-(methylenebis(oxy))-, hydrochloride, (1-alpha,2-beta)-
  • Licorin hydrochloride
  • Lycorine HCl
  • Lycorine hydrochloride
  • UNII-58F70VH0HS

Systematic Name

  • Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-, hydrochloride

Registry Numbers

CAS Registry Number

  • 2188-68-3

FDA UNII

  • 58F70VH0HS

System Generated Number

  • 0002188683

Molecular Formulas

Molecular Formula

  • C16-H17-N-O4.Cl-H

Molecular Formula Fragments

  • C16-H17-N-O4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1

InChIKey

VUVNTYCHKZBOMV-NVJKKXITSA-N

Smiles

c1c2c(cc3[C@H]4[C@H]5C(CC[N@@]5Cc13)=C[C@@H](O)[C@H]4O)OCO2.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 117mg/kg (117mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 intravenous 123mg/kg (123mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 oral 230mg/kg (230mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.