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Substance Name: Pexelizumab [USAN:INN:BAN]
RN: 219685-93-5
UNII: CHZ6OLQ3UU

Note

  • A 25 kDa recombinant, humanized, single-chain antibody that binds to human C5 with a very high affinity & thereby blocks C5 cleavage by C5 convertases; for treatment of patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass.

Molecular Formula

  • Unspecified
 

Classification Code

  • Complement Inhibitor used to Reduce the Impact of Complement-Mediated Injuries Sustained During Cardiopulmonary Bypass (Humanized Monoclonal Antibody)
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Names and Synonyms

Name of Substance

  • Pexelizumab [USAN:INN:BAN]

Synonyms

  • h5G1.1 scFv
  • h5G1.1 scFv (CDR)
  • h5G1.1-scFv
  • Immunoglobulin, anti-(human complement C5 alpha-chain) (human-mouse monoclonal 5G1.1-SC single chain)
  • Pexelizumab
  • UNII-CHZ6OLQ3UU

Systematic Name

  • Immunoglobulin, anti-(human complement C5 alpha-chain) (human-mouse monoclonal 5G11-SC single chain)

Registry Numbers

CAS Registry Number

  • 219685-93-5

FDA UNII

  • CHZ6OLQ3UU

System Generated Number

  • 0219685935