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Substance Name: Tiomesterone [INN:BAN]
RN: 2205-73-4
UNII: W5K3712F4H
InChIKey: YUOZKOLALXNELS-SQVYRKCQSA-N

Classification Codes

  • Hormone
  • Reproductive Effect

Molecular Formula

  • C24-H34-O4-S2

Molecular Weight

  • 450.6606
 
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Names and Synonyms

Name of Substance

  • Thiomesterone
  • Tiomesterone
  • Tiomesterone [INN:BAN]

Synonyms

  • EINECS 218-614-4
  • Embadol
  • Emdabol
  • Emdabolin
  • Protabol
  • ST A 307
  • STA-307
  • Thiomesterone
  • Thiomestrone
  • Tiomesterona
  • Tiomesterona [INN-Spanish]
  • Tiomesterone
  • Tiomesteronum
  • Tiomesteronum [INN-Latin]
  • UNII-W5K3712F4H

Systematic Names

  • 1alpha,7alpha-Diacetylthio 17beta-hydroxy-17-methylandrost-4-en-3-one
  • Androst-4-en-3-one, 17-beta-hydroxy-1-alpha,7-alpha-dimercapto-17-methyl-, 1,7-diacetate
  • Tiomesterone

Registry Numbers

CAS Registry Number

  • 2205-73-4

FDA UNII

  • W5K3712F4H

System Generated Number

  • 0002205734

Structure Descriptors

InChI

1S/C24H34O4S2/c1-13(25)29-19-11-15-10-16(27)12-20(30-14(2)26)24(15,5)18-6-8-22(3)17(21(18)19)7-9-23(22,4)28/h10,17-21,28H,6-9,11-12H2,1-5H3/t17-,18-,19+,20-,21-,22-,23-,24-/m0/s1

InChIKey

YUOZKOLALXNELS-SQVYRKCQSA-N

Smiles

CC(=O)S[C@@H]1CC2=CC(=O)C[C@H](SC(=O)C)[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@]4(C)O)[C@H]13

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo oral 2150mg/kg (2150mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 330, 1964.
rat LD50 oral > 10gm/kg (10000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 721, 1967.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 205.5 deg C   EXP
log P (octanol-water) 2.360 (none)   EST
Atmospheric OH Rate Constant 1.50E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.