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Substance Name: Ruplizumab [USAN:INN]
RN: 220651-94-5
UNII: 562JQF15GN

 

Classification Codes

  • Monoclonal Antibody
  • Treatment of Immune Thrombocytopenic Purpura
  • Treatment of Immune Thrombocytopenic Purpura and Systemic Lupus Erythematosus (Humanized Monoclonal Antibody)
  • Treatment of Systemic Lupus Erythematosus
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Names and Synonyms

Name of Substance

  • Ruplizumab [USAN:INN]

Synonyms

  • BG 9588
  • BG9588
  • Hu5c8
  • Immunoglobulin G1 (human-mouse monoclonal 5c8 gamma1-chain anti-human CD40 ligand), disulfide with human-mouse monoclonal 5c8 kappa-chain, dimer. Molecular weight is approximately 145,448 daltons (with two additional N-linked glycans consisting of several glycoform species with an average molecular weight of approximately 1500 daltons)
  • Immunoglobulin G1, (anti-human CD40 ligand) (human-mouse monoclonal 5c8 gamma1-chain), disulfide with human-mouse monoclonal 5c8 kappa-chain, dimer
  • Ruplizumab
  • UNII-562JQF15GN

Systematic Name

  • Immunoglobulin G1, (anti-human CD40 ligand)(human-mouse monoclonal 5c8 gamma1-chain), disulfide with human-mouse monoclonal 5c8 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 220651-94-5

FDA UNII

  • 562JQF15GN

System Generated Number

  • 0220651945