Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Mofebutazone [INN:DCF]
RN: 2210-63-1
UNII: SPW36WUI5Z
InChIKey: REOJLIXKJWXUGB-UHFFFAOYSA-N

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Peripheral Nervous System Agents
  • Sensory System Agents

Molecular Formula

  • C13-H16-N2-O2

Molecular Weight

  • 232.2814
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Mofebutazone
  • Mofebutazone [INN:DCF]

Synonyms

  • 2 Fdbp
  • 2-Phenyl-3,5-dihydroxy-4-butylpyrazolidine
  • 4-Butyl-1-phenyl-3,5-dioxopyrazolidine
  • 4-Butyl-1-phenyl-3,5-pyrazolidinedione
  • 5-24-05-00400 (Beilstein Handbook Reference)
  • Arcobutine
  • Arcomonol tablets
  • BRN 0213056
  • Butazone
  • Corbuton
  • EINECS 218-641-1
  • Mobutazon
  • Mobutazone
  • Mobuzon
  • Mofebutazona
  • Mofebutazona [INN-Spanish]
  • Mofebutazone
  • Mofebutazonum
  • Mofebutazonum [INN-Latin]
  • Monazan
  • Monobutyl
  • Monofen
  • Monomil
  • Monophenylbutazone
  • Monorheumetten
  • Monozon
  • Mophebutazone
  • Mozol
  • NSC 73725
  • Reumatox
  • UNII-SPW36WUI5Z

Systematic Names

  • 3,5-Pyrazolidinedione, 4-butyl-1-phenyl-
  • 4-Butyl-1-phenyl-3,5-pyrazolidinedione
  • Mofebutazone

Registry Numbers

CAS Registry Number

  • 2210-63-1

FDA UNII

  • SPW36WUI5Z

Related Registry Number

  • 41468-34-2 (hydrochloride salt)

System Generated Number

  • 0002210631

Structure Descriptors

InChI

1S/C13H16N2O2/c1-2-3-9-11-12(16)14-15(13(11)17)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3,(H,14,16)

InChIKey

REOJLIXKJWXUGB-UHFFFAOYSA-N

Smiles

CCCCC1C(=O)NN(C1=O)c2ccccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 700mg/kg (700mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Scientia Pharmaceutica. Vol. 37, Pg. 185, 1969.
mouse LD50 intravenous 600mg/kg (600mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 233, Pg. 365, 1958.
mouse LD50 subcutaneous 920mg/kg (920mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Scientia Pharmaceutica. Vol. 37, Pg. 185, 1969.
rat LD50 intraperitoneal 848mg/kg (848mg/kg)   Farmaco, Edizione Scientifica. Vol. 14, Pg. 347, 1959.
rat LD50 oral 1750mg/kg (1750mg/kg)   Pharmaceutica Acta Helvetiae. Vol. 39, Pg. 155, 1964.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 102.5 deg C   EXP
log P (octanol-water) 1.900 (none)   EST
Atmospheric OH Rate Constant 2.60E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.