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Substance Name: GW-475151
RN: 221323-43-9
UNII: O4007HW00C
InChIKey: MEDXAFZZWXHGBT-UAGQMJEPSA-N

Note

  • Inhibits neutrophil elastase; GW-475151 is the (3S,3aS,6aR)-isomer.

Molecular Formula

  • C19-H28-N4-O5-S

Molecular Weight

  • 424.5192
 
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Names and Synonyms

Name of Substance

  • GW-475151

Synonyms

  • GW-475151
  • Pyrrolo(3,2-b)pyrrol-2(1H)-one, hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-((2-(1-pyrrolidinylmethyl)-4-oxazolyl)carbonyl)-, (3R,3aR,6aS)-rel-
  • UNII-O4007HW00C

Registry Numbers

CAS Registry Number

  • 221323-43-9

FDA UNII

  • O4007HW00C

System Generated Number

  • 0221323439

Structure Descriptors

InChI

1S/C19H28N4O5S/c1-12(2)16-17-14(23(19(16)25)29(3,26)27)6-9-22(17)18(24)13-11-28-15(20-13)10-21-7-4-5-8-21/h11-12,14,16-17H,4-10H2,1-3H3/t14-,16+,17-/m0/s1

InChIKey

MEDXAFZZWXHGBT-UAGQMJEPSA-N

Smiles

CC(C)[C@@H]1[C@@H]2[C@H](CCN2C(=O)c3coc(n3)CN4CCCC4)N(C1=O)S(=O)(=O)C