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Substance Name: Elexacaftor [USAN]
RN: 2216712-66-0
UNII: RRN67GMB0V
InChIKey: MVRHVFSOIWFBTE-INIZCTEOSA-N
Note
- Cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore Phe508del CFTR protein function in patients with cystic fibrosis when administered with tezacaftor and ivacaftor.
Molecular Formula
- C26-H34-F3-N7-O4-S
Molecular Weight
- 597.6596
Classification Codes
- Chloride Channel Agonists
- Membrane Transport Modulators
- Treatment of Cystic Fibrosis
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Names and Synonyms
Name of Substance
- Elexacaftor [USAN]
- VX-445
Synonyms
- 3-Pyridinecarboxamide, N-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-((4S)-2,2,4-trimethyl-1-pyrrolidinyl)-
- Elexacaftor
- UNII-RRN67GMB0V
- VX-445
- WHO 11180
Registry Numbers
CAS Registry Number
- 2216712-66-0
FDA UNII
- RRN67GMB0V
System Generated Number
- 2216712660