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Substance Name: Fencamfamin hydrochloride
RN: 2240-14-4
UNII: 0M1J60BWEX
InChIKey: CVFSMSTXULJISA-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H21-N.Cl-H

Molecular Weight

  • 251.799
 
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Names and Synonyms

Name of Substance

  • Fencamfamin hydrochloride
  • Fencamfamine hydrochloride

Synonyms

  • 2-Aethylamino-3-phenyl-nor-camphan
  • 2-Aethylamino-3-phenyl-nor-camphan hydrochlorid
  • 2-Aethylamino-3-phenyl-nor-camphan hydrochlorid [German]
  • 2-Aethylamino-3-phenyl-nor-camphan [German]
  • 2-Ethylamino-3-phenyl-norcamphane hydrochloride
  • 2-Ethylamino-3-phenylbicyclo(2.2.1)heptane hydrochloride
  • Altimine
  • EINECS 218-805-2
  • Envitrol
  • Fencamfamin HCl
  • Fencamfamin hydrochloride
  • Fencamfamine hydrochloride
  • Glucoenergan
  • H 610
  • NSC 172254
  • Phencamine
  • Reactivan
  • UNII-0M1J60BWEX

Systematic Names

  • 2-Norbornanamine, N-ethyl-3-phenyl-, hydrochloride
  • 3-Phenyl-N-ethyl-2-norbornanamine hydrochloride
  • Bicyclo(2.2.1)heptan-2-amine, N-ethyl-3-phenyl-, hydrochloride (9CI)
  • Fencamfamin hydrochloride

Registry Numbers

CAS Registry Number

  • 2240-14-4

FDA UNII

  • 0M1J60BWEX

Related Registry Number

  • 1209-98-9 (Parent)

System Generated Number

  • 0002240144

Molecular Formulas

Molecular Formula

  • C15-H21-N.Cl-H

Molecular Formula Fragments

  • C15-H21-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H21N.ClH/c1-2-16-15-13-9-8-12(10-13)14(15)11-6-4-3-5-7-11;/h3-7,12-16H,2,8-10H2,1H3;1H

InChIKey

CVFSMSTXULJISA-UHFFFAOYSA-N

Smiles

C1[C@@H]2CC[C@@H]1[C@@H]([C@@H]2c1ccccc1)NCC.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 34mg/kg (34mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
dog LD50 intravenous 15mg/kg (15mg/kg) BEHAVIORAL: ATAXIA

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
dog LD50 oral 30mg/kg (30mg/kg) BEHAVIORAL: ATAXIA

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
mouse LD50 intravenous 15700ug/kg (15.7mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
mouse LD50 oral 135mg/kg (135mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
mouse LD50 subcutaneous 85500ug/kg (85.5mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
rat LD50 intravenous 23500ug/kg (23.5mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.
rat LD50 oral 83mg/kg (83mg/kg)   Journal of Pediatrics. Vol. 69, Pg. 663, 1966.
rat LD50 subcutaneous 68500ug/kg (68.5mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 20, 1961.