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Substance Name: Cinacalcet [USAN:INN:BAN]
RN: 226256-56-0
UNII: UAZ6V7728S
InChIKey: VDHAWDNDOKGFTD-MRXNPFEDSA-N

Note

  • A calcimimetic for treatment for secondary hyperparathyroidism of end-stage renal disease; KRN 1493 is also referred to as AMG073.

Molecular Formula

  • C22-H22-F3-N

Molecular Weight

  • 357.4168
 

Classification Codes

  • Calcimimetic
  • Treatment of Hyperparathyroidism and Related Disorders, such as Hypercalcemia (Reduction of PTH Secretion Through Modulation of Calcium Ion Receptors on Parathyroid Cells)
  • Treatment of Hyperthyroidism

Names and Synonyms

Name of Substance

  • Cinacalcet [USAN:INN:BAN]

Synonyms

  • AMG 073
  • AMG073
  • Cinacalcet
  • HSDB 7318
  • Mimpara
  • N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
  • Parareg
  • UNII-UAZ6V7728S

Systematic Names

  • 1-Naphthalenemethanamine, alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-, (alphaR)-
  • N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine

Registry Numbers

CAS Registry Number

  • 226256-56-0

FDA UNII

  • UAZ6V7728S

Related Registry Number

  • 364782-34-3 (Hydrochloride)

System Generated Number

  • 0226256560

Structure Descriptors

InChI

1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1

InChIKey

VDHAWDNDOKGFTD-MRXNPFEDSA-N

Smiles

C[C@H](c1cccc2c1cccc2)NCCCc3cccc(c3)C(F)(F)F