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Substance Name: Rafoxanide [USAN:INN:BAN]
RN: 22662-39-1
UNII: 22F4FLA7DH
InChIKey: NEMNPWINWMHUMR-UHFFFAOYSA-N

Note

  • Veterinary anthelmintic for grazing animals; used to treat fluke, hookworm and other infestations.

Molecular Formula

  • C19-H11-Cl2-I2-N-O3

Molecular Weight

  • 626.006
 

Classification Codes

  • Agricultural Chemical
  • Anthelmintic
  • Anthelmintics
  • Anti-Infective Agents
  • Antinematodal Agents
  • Antiparasitic Agents
  • Antiplatyhelmintic Agents
  • Insect Attractant, Repellent and Chemosterilant
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Names and Synonyms

Name of Substance

  • Rafoxanide
  • Rafoxanide [USAN:INN:BAN]

MeSH Heading

  • Rafoxanide

Synonyms

  • 3'-Chlor-4'-(4-chlorphenoxy)-3,5-diiodsalicylanilid
  • 3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide
  • AI3-29020
  • Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-
  • Bovanide
  • BRN 2228187
  • Disalan
  • Duofas
  • EINECS 245-148-9
  • Flukanide
  • MK-990
  • NSC 355278
  • Rafoxanida
  • Rafoxanida [INN-Spanish]
  • Rafoxanide
  • Rafoxanidum
  • Rafoxanidum [INN-Latin]
  • Ranide
  • Ranide, veterinary
  • UNII-22F4FLA7DH

Systematic Names

  • Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-
  • Rafoxanide
  • Salicylanilide, 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodo-

Registry Numbers

CAS Registry Number

  • 22662-39-1

FDA UNII

  • 22F4FLA7DH

System Generated Number

  • 0022662391

Structure Descriptors

InChI

1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

InChIKey

NEMNPWINWMHUMR-UHFFFAOYSA-N

Smiles

c1(C(Nc2cc(c(Oc3ccc(Cl)cc3)cc2)Cl)=O)c(c(cc(c1)I)I)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LDLo unreported 80mg/kg (80mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Revue d'Elevage et de Medicine Veterinaire des Pays Tropicaux. Vol. 29, Pg. 31, 1976.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 169 deg C   EXP
log P (octanol-water) 8.140 (none)   EST
Atmospheric OH Rate Constant 8.30E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.