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Substance Name: Fosamprenavir [INN]
RN: 226700-79-4
UNII: WOU1621EEG
InChIKey: MLBVMOWEQCZNCC-OEMFJLHTSA-N

Note

  • A prodrug of the protease inhibitor amprenavir.

Molecular Formula

  • C25-H36-N3-O9-P-S

Molecular Weight

  • 585.6114
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Enzyme Inhibitors
  • HIV Protease Inhibitors
  • Protease Inhibitors

Names and Synonyms

Name of Substance

  • Fosamprenavir
  • Fosamprenavir [INN]

Synonyms

  • (3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester
  • FOS-APV
  • Fosamprenavir
  • FPV
  • GW 433908
  • GW433908
  • HSDB 7340
  • Telzir
  • UNII-WOU1621EEG
  • VX 175

Systematic Name

  • Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester

Registry Numbers

CAS Registry Number

  • 226700-79-4

FDA UNII

  • WOU1621EEG

System Generated Number

  • 0226700794

Structure Descriptors

InChI

1S/C25H36N3O9PS/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32)/t21-,23-,24+/m0/s1

InChIKey

MLBVMOWEQCZNCC-OEMFJLHTSA-N

Smiles

CC(C)CN(C[C@H]([C@H](Cc1ccccc1)NC(=O)O[C@H]2CCOC2)OP(=O)(O)O)S(=O)(=O)c3ccc(cc3)N