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Substance Name: Fosamprenavir sodium [USAN]
RN: 226700-80-7
UNII: XSG28FSA0W
InChIKey: FZMGUXZZROZJIT-KMIZVRHLSA-L

Note

  • A prodrug of the protease inhibitor amprenavir

Classification Code

  • Antiviral (HIV Protease Inhibitor)

Molecular Formula

  • C25-H36-N3-O9-P-S.2Na

Molecular Weight

  • 629.5756
 

Names and Synonyms

Name of Substance

  • Fosamprenavir sodium [USAN]

Synonyms

  • (3S)-Tetrahydro-3-furyl ((alphaS)-alpha-((1R)-1-hydroxy-2-(N(sup 1)-isobutylsulfanilamido)ethyl)phenethyl)carbamate, disodium phosphate (ester)
  • Fosamprenavir sodium
  • GW 433908A
  • UNII-XSG28FSA0W
  • VX 175

Systematic Name

  • Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester, disodium salt

Registry Numbers

CAS Registry Number

  • 226700-80-7

FDA UNII

  • XSG28FSA0W

System Generated Number

  • 0226700807

Molecular Formulas

Molecular Formula

  • C25-H36-N3-O9-P-S.2Na

Molecular Formula Fragments

  • C25-H36-N3-O9-P-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

InChI=1S/C25H36N3O9PS.2Na/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);;/q;2*+1/p-2/t21-,23-,24+;;/m0../s1

InChIKey

FZMGUXZZROZJIT-KMIZVRHLSA-L

Smiles

[Na+].[Na+].CC(C)CN(C[C@@H](OP(=O)([O-])[O-])[C@H](Cc1ccccc1)NC(=O)O[C@H]2CCOC2)S(=O)(=O)c3ccc(N)cc3