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Substance Name: Vamidothion [BSI:ISO]
RN: 2275-23-2
UNII: H1G712H762
InChIKey: LESVOLZBIFDZGS-UHFFFAOYSA-N

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Fungicide, Bactericide, Wood Preservative
  • Insecticide
  • Mutation Data

Molecular Formula

  • C8-H18-N-O4-P-S2

Molecular Weight

  • 287.3392
 
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Names and Synonyms

Results Name

  • Vamidothion [BSI:ISO]

Name of Substance

  • Vamidothion
  • Vamidothion [BSI:ISO]

Synonyms

  • 10465 rp
  • 2-(2-Dimethoxyphosphinoylthioethylthio)-N-methylpropionamide
  • AI3-25761
  • American cyanamid-43073
  • BRN 2651123
  • Caswell No. 379A
  • CCRIS 1305
  • Dimethyl S-(2-(1-methylcarbamoylethylthio)ethyl) phosphorothiolate
  • EINECS 218-894-8
  • ENT 26,613
  • EPA Pesticide Chemical Code 379200
  • HSDB 6746
  • Kilval
  • N-Methyl O,O-dimethylthiolophosphoryl-5-thia-3-methyl-2-valeramide
  • N-Methyl-3-thia-2-methyl-valeramid der O,O-dimethylthiolphosphorsaeure
  • N-Methyl-3-thia-2-methyl-valeramid der O,O-dimethylthiolphosphorsaeure [German]
  • NPH 83
  • O,O-Dimethyl phosphorothioate S-ester with 2-((2-mercaptoethyl)thio)-N-methylpropionamide
  • O,O-Dimethyl S-(2-((1-methyl-2-(methylamino)-2-oxoethyl)thio)ethyl) phosphorothioate (9CI)
  • O,O-Dimethyl S-(2-(1-methylcarbamoylethylthio)ethyl) phosphorothioate
  • O,O-Dimethyl S-2-(1-N-methylcarbamoylethylmercapto)ethyl thiophosphate
  • R.P. 10,465
  • RP-9895
  • Trucidor
  • UNII-H1G712H762
  • Vamidoate
  • Vamidothion

Systematic Names

  • Phosphorothioic acid, O,O-dimethyl ester, S-ester with 2-((2-mercaptoethyl)thio)-N-methylpropionamide
  • Phosphorothioic acid, O,O-dimethyl S-(2-((1-methyl-2-(methylamino)-2-oxoethyl)thio)ethyl) ester
  • Vamidothion

Registry Numbers

CAS Registry Number

  • 2275-23-2

FDA UNII

  • H1G712H762

System Generated Number

  • 0002275232

Structure Descriptors

InChI

1S/C8H18NO4PS2/c1-7(8(10)9-2)15-5-6-16-14(11,12-3)13-4/h7H,5-6H2,1-4H3,(H,9,10)

InChIKey

LESVOLZBIFDZGS-UHFFFAOYSA-N

Smiles

S(P(OC)(OC)=O)CCS[C@@H](C)C(NC)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 35mg/kg (35mg/kg)   Pesticide Manual. Vol. 9, Pg. 856, 1991.
cat LD50 unreported 117mg/kg (117mg/kg) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED

BEHAVIORAL: COMA

BEHAVIORAL: ATAXIA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(3), Pg. 107, 1976.
dog LD50 oral 110mg/kg (110mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig LD50 oral 85mg/kg (85mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig LD50 unreported 85mg/kg (85mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
mouse LD50 oral 40mg/kg (40mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Meditsinskii Zhurnal Uzbekistana. Vol. (8), Pg. 65, 1972.
mouse LD50 skin 1460mg/kg (1460mg/kg)   Yakkyoku. Pharmacy. Vol. 37, Pg. 1621, 1986.
mouse LD50 unreported 43mg/kg (43mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
rabbit LD50 oral 160mg/kg (160mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(2), Pg. 58, 1970.
rabbit LD50 skin 1160mg/kg (1160mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LC50 inhalation 1730mg/m3/4H (1730mg/m3)   Pesticide Manual. Vol. 9, Pg. 856, 1991.
rat LD50 oral 64mg/kg (64mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 233, 1976.
rat LD50 unreported 64mg/kg (64mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 43 deg C   EXP
log P (octanol-water) 0.160 (none)   EST
Water Solubility 1.00E+06 mg/L 20 EXP
Henry's Law Constant 8.60E-16 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.16E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.