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Substance Name: Aspartame [USAN:INN:BAN:NF]
RN: 22839-47-0
UNII: Z0H242BBR1
InChIKey: IAOZJIPTCAWIRG-QWRGUYRKSA-N
Note
- Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID.
Molecular Formula
- C14-H18-N2-O5
Molecular Weight
- 294.3052
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Flavoring Agents
- Food Additives
- Human Data
- Reproductive Effect
- Sweetener
- Sweetening Agents
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Names and Synonyms
Name of Substance
- Aspartame
- Aspartame [USAN:INN:BAN:NF]
MeSH Heading
- Aspartame
Synonyms
- 1-Methyl N-L-alpha-aspartyl-L-phenylalanate
- 1-Methyl N-L-alpha-aspartyl-L-phenylalanine
- 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester
- 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, stereoisomer
- 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid
- APM
- Asp-phe-ome
- Aspartam
- Aspartam [INN-French]
- Aspartame
- Aspartame, L,L-alpha-
- Aspartamo
- Aspartamo [INN-Spanish]
- Aspartamum
- Aspartamum [INN-Latin]
- Aspartylphenylalanine methyl ester
- Canderel
- CCRIS 5456
- Dipeptide sweetener
- EINECS 245-261-3
- Equal
- HSDB 3915
- L-Aspartyl-L-phenylalanine methyl ester
- L-Phenylalanine, N-L-alpha-aspartyl-, 1-methyl ester
- Methyl aspartylphenylalanate
- Methyl L-alpha-aspartyl-L-phenylalanate
- Methyl L-aspartyl-L-phenylalanine
- Methyl N-L-alpha-aspartyl-L-phenylalaninate
- N-L-alpha-Aspartyl-L-phenylalanine 1-methyl ester
- NSC 758953
- Nutrasweet
- SC 18862
- SC-18862
- Succinamic acid, 3-amino-N-(alpha-carboxyphenethyl)-, N-methyl ester, stereoisomer
- Sweet dipeptide
- Tri-sweet
- UNII-Z0H242BBR1
Systematic Names
- Aspartame
- L-Phenylalanine, L-alpha-aspartyl-, 2-methyl ester
- L-Phenylalanine, N-L-alpha-aspartyl-, 1-methyl ester
- Succinamic acid, 3-amino-N-(alpha-carboxyphenethyl)-, N-methyl ester, stereoisomer
Superlist Name
- Aspartame
Registry Numbers
CAS Registry Number
- 22839-47-0
FDA UNII
- Z0H242BBR1
Other Registry Numbers
- 172964-81-7
- 53906-69-7
- 7421-84-3
System Generated Number
- 0022839470
Structure Descriptors
InChI
InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1InChIKey
IAOZJIPTCAWIRG-QWRGUYRKSA-NSmiles
COC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 5gm/kg (5000mg/kg) | Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | |
mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | |
rat | LD50 | intraperitoneal | > 5gm/kg (5000mg/kg) | Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | |
rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | |
women | TDLo | oral | 3710ug/kg (3.71mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" | Annals of Internal Medicine. Vol. 104, Pg. 207, 1986. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 246.5 | deg C | EXP | |
log P (octanol-water) | 0.070 | (none) | EST | |
Vapor Pressure | 4.54E-12 | mm Hg | 25 | EST |
Henry's Law Constant | 2.53E-18 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 5.56E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.