Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Neferine
RN: 2292-16-2
InChIKey: MIBATSHDJRIUJK-ROJLCIKYSA-N

Note

  • Isolated from green seed embryo of Nelumbo nucifera Gaertn.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C38-H44-N2-O6

Molecular Weight

  • 624.774
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Neferine

Synonyms

  • BRN 1523459
  • Neferin
  • Neferine

Systematic Name

  • Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-((1,2,3,4-tetrahydro-6-methoxy-1-((4-methoxyphenyl)methyl)-2-methyl-7-isoquinolinyl)oxy)-

Registry Numbers

CAS Registry Number

  • 2292-16-2

System Generated Number

  • 0002292162

Structure Descriptors

InChI

1S/C38H44N2O6/c1-39-15-14-27-21-36(44-5)38(23-30(27)31(39)17-24-7-10-28(42-3)11-8-24)46-34-19-25(9-12-33(34)41)18-32-29-22-37(45-6)35(43-4)20-26(29)13-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3/t31-,32-/m1/s1

InChIKey

MIBATSHDJRIUJK-ROJLCIKYSA-N

Smiles

c1(c(cc(cc1)C[C@H]1[N@@](CCc2cc(c(cc12)OC)OC)C)Oc1c(cc2CC[N@@]([C@@H](c2c1)Cc1ccc(cc1)OC)C)OC)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 26mg/kg (26mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 217, 1988.