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Substance Name: (-)-Chlorpheniramine maleate
RN: 23095-76-3
UNII: 5T8587JTSU
InChIKey: DBAKFASWICGISY-HFNHQGOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C16-H19-Cl-N2.C4-H4-O4

Molecular Weight

  • 390.8647
 
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Names and Synonyms

Results Name

  • (-)-Chlorpheniramine maleate

Name of Substance

  • Chlorpheniramine maleate, (-)-

Synonyms

  • (-)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate
  • (-)-Chlorpheniramine maleate
  • (R)-(-)-Chlorpheniramine maleate
  • 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (R)-, (Z)-2-butenedioate (1:1)
  • L-Chlorpheniramine maleate
  • UNII-5T8587JTSU

Systematic Name

  • Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (-)-

Registry Numbers

CAS Registry Number

  • 23095-76-3

FDA UNII

  • 5T8587JTSU

System Generated Number

  • 0023095763

Molecular Formulas

Molecular Formula

  • C16-H19-Cl-N2.C4-H4-O4

Molecular Formula Fragments

  • C16-H19-Cl-N2
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m1./s1

InChIKey

DBAKFASWICGISY-HFNHQGOYSA-N

Smiles

CN(C)CC[C@H](c1ccc(cc1)Cl)c2ccccn2.C(=C\C(=O)O)\C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 176mg/kg (176mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Journal of Pharmacology and Experimental Therapeutics. Vol. 124, Pg. 347, 1958.