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Substance Name: Guanabenz hydrochloride
RN: 23113-43-1
InChIKey: UNWWUUPHJRAOMZ-GAYQJXMFSA-N

Note

  • An alpha-2 selective adrenergic agonist used as an antihypertensive agent.

Molecular Formula

  • C8-H8-Cl2-N4.Cl-H

Molecular Weight

  • 267.5461
 
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Names and Synonyms

Results Name

  • Guanabenz hydrochloride

Synonyms

  • 2-(2,6-Dichlorobenzylidene)hydrazinecarboximidamide hydrochloride
  • Guanabenz HCl
  • Guanabenz hydrochloride
  • Guanoxabenzhydrochloride
  • WY-8678 hydrochloride

Systematic Name

  • Hydrazinecarboximidamide, 2-(2,6-dichlorobenzylidene)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 23113-43-1

System Generated Number

  • 0023113431

Molecular Formulas

Molecular Formula

  • C8-H8-Cl2-N4.Cl-H

Molecular Formula Fragments

  • C8-H8-Cl2-N4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C8H8Cl2N4.ClH/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12;/h1-4H,(H4,11,12,14);1H/b13-4+;

InChIKey

UNWWUUPHJRAOMZ-GAYQJXMFSA-N

Smiles

N(/N=C/c1c(cccc1Cl)Cl)C(=N)N.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT
Yakugaku Zasshi. Journal of Pharmacy. Vol. 95, Pg. 966, 1975.