Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Lapatinib [INN:BAN]
RN: 231277-92-2
UNII: 0VUA21238F
InChIKey: BCFGMOOMADDAQU-UHFFFAOYSA-N

Note

  • An EGFR-ErbB-2 inhibitor.

Molecular Formula

  • C29-H26-Cl-F-N4-O4-S

Molecular Weight

  • 581.065
 

Classification Codes

  • Antineoplastic
  • Antineoplastic Agents
  • Dual EGFR/erbB2 Inhibitors
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors
  • Tyrosine Kinase Inhibitors

Names and Synonyms

Name of Substance

  • Lapatinib [INN:BAN]

Synonyms

  • GSK 572016
  • GW 572016
  • GW572016
  • HSDB 8209
  • Lapatinib
  • Tykerb
  • UNII-0VUA21238F

Systematic Name

  • 4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-

Registry Numbers

CAS Registry Number

  • 231277-92-2

FDA UNII

  • 0VUA21238F

System Generated Number

  • 0231277922

Structure Descriptors

InChI

1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)

InChIKey

BCFGMOOMADDAQU-UHFFFAOYSA-N

Smiles

c1cc2ncnc(Nc3ccc(c(c3)Cl)OCc3cccc(c3)F)c2cc1c1oc(cc1)CNCCS(=O)(=O)C