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Substance Name: Ifenprodil [INN:DCF]
RN: 23210-56-2
UNII: R8OE3P6O5S
InChIKey: UYNVMODNBIQBMV-UHFFFAOYSA-N

Note

  • NMDA receptor antagonist.

Molecular Formula

  • C21-H27-N-O2

Molecular Weight

  • 325.4493
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic alpha-Antagonists
  • Adrenergic Antagonists
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Excitatory Amino Acid Agents
  • Excitatory Amino Acid Antagonists
  • Neurotransmitter Agents
  • Vasodilator Agents
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Names and Synonyms

Name of Substance

  • Ifenprodil
  • Ifenprodil [INN:DCF]

Synonyms

  • 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol
  • 4-Benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol
  • Creocral
  • Dilvax
  • EINECS 245-491-4
  • Ifenprodil
  • Ifenprodilum
  • Ifenprodilum [INN-Latin]
  • RC 61-91
  • UNII-R8OE3P6O5S
  • Vadilex

Systematic Names

  • 1-Piperidineethanol, 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-
  • 1-Piperidineethanol, alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)- (9CI)
  • 4-Benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol
  • alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine ethanol
  • Ifenprodil

Registry Numbers

CAS Registry Number

  • 23210-56-2

FDA UNII

  • R8OE3P6O5S

Other Registry Number

  • 925913-11-7

System Generated Number

  • 0023210562

Structure Descriptors

InChI

1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3

InChIKey

UYNVMODNBIQBMV-UHFFFAOYSA-N

Smiles

CC(C(c1ccc(cc1)O)O)N2CCC(CC2)Cc3ccccc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 320mg/kg (320mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 1992, 1971.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 114 deg C   EXP
log P (octanol-water) 3.900 (none)   EST
Atmospheric OH Rate Constant 1.71E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.