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Substance Name: Deprenyl
RN: 2323-36-6
UNII: DPF682Q08V
InChIKey: MEZLKOACVSPNER-UHFFFAOYSA-N

Note

  • A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

Molecular Formula

  • C13-H17-N

Molecular Weight

  • 187.2843
 

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect
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Names and Synonyms

Results Name

  • Deprenyl

Name of Substance

  • (+-)-Deprenyl

Synonyms

  • Deprenil
  • Deprenyl
  • N,alpha-Dimethyl-N-2-propynylbenzeneethanamine
  • N,alpha-Dimethyl-N-2-propynylphenethylamine
  • UNII-DPF682Q08V

Systematic Names

  • Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl- (9CI)
  • Phenethylamine, N,alpha-dimethyl-N-2-propynyl-

Registry Numbers

CAS Registry Number

  • 2323-36-6

FDA UNII

  • DPF682Q08V

System Generated Number

  • 0002323366

Structure Descriptors

InChI

1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3

InChIKey

MEZLKOACVSPNER-UHFFFAOYSA-N

Smiles

CC(Cc1ccccc1)N(C)CC#C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   Journal of Medicinal Chemistry. Vol. 31, Pg. 1253, 1988.