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Substance Name: Thioproperazine mesylate
RN: 2347-80-0
UNII: 71P630M192
InChIKey: QPMDKXBBAVQDCB-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data

Molecular Formula

  • C22-H30-N4-O2-S2.2C-H4-O3-S

Molecular Weight

  • 638.8482
 
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Names and Synonyms

Name of Substance

  • Thioproperazine dimethanesulfonate
  • Thioproperazine mesylate

Synonyms

  • EINECS 219-074-2
  • Mageptyl
  • Majeptil
  • Thioperazine dimethanesulfonate
  • Thioperazine methanesulfate
  • Thioproperazine bis-methanesulfonate
  • Thioproperazine dimethanesulfonate
  • Thioproperazine mesilate
  • Thioproperazine mesylate
  • Thioproperazine methanesulfonate
  • UNII-71P630M192
  • Vontil

Systematic Names

  • Phenothiazine-2-sulfonamide, N,N-dimethyl-10-(3-(4-methyl-1-piperazinyl)propyl)-, dimethanesulfonate
  • Thioproperazine dimesilate

Registry Numbers

CAS Registry Number

  • 2347-80-0

FDA UNII

  • 71P630M192

System Generated Number

  • 0002347800

Molecular Formulas

Molecular Formula

  • C22-H30-N4-O2-S2.2C-H4-O3-S

Molecular Formula Fragments

  • C-H4-O3-S
  • C22-H30-N4-O2-S2
  • COMPONENT

Structure Descriptors

InChI

1S/C22H30N4O2S2.2CH4O3S/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25;2*1-5(2,3)4/h4-5,7-10,17H,6,11-16H2,1-3H3;2*1H3,(H,2,3,4)

InChIKey

QPMDKXBBAVQDCB-UHFFFAOYSA-N

Smiles

CN1CCN(CC1)CCCN2c3ccccc3Sc4c2cc(cc4)S(=O)(=O)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 115mg/kg (115mg/kg)   Psychopharmacologia Vol. 12, Pg. 142, 1968.
mouse LD50 intravenous 70mg/kg (70mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 52, 1972.
mouse LD50 oral 800mg/kg (800mg/kg)   Drugs in Japan Vol. 6, Pg. 456, 1982.
mouse LD50 subcutaneous 500mg/kg (500mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 52, 1972.
rat LD50 intraperitoneal 59mg/kg (59mg/kg)   Psychopharmacologia Vol. 12, Pg. 142, 1968.
rat LD50 intravenous 45mg/kg (45mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 52, 1972.
rat LD50 oral 750mg/kg (750mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 52, 1972.
rat LD50 subcutaneous 1250mg/kg (1250mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 52, 1972.