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Substance Name: Levosulpiride [INN]
RN: 23672-07-3
UNII: JTG7R315LK
InChIKey: BGRJTUBHPOOWDU-NSHDSACASA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H23-N3-O4-S

Molecular Weight

  • 341.4297
 
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Names and Synonyms

Name of Substance

  • Levosulpiride
  • Levosulpiride [INN]

Synonyms

  • (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • (S)-(-)-N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoyl-, S-(-)-
  • Levopraid
  • Levosulpirida
  • Levosulpirida [INN-Spanish]
  • Levosulpiride
  • Levosulpiridum
  • Levosulpiridum [INN-Latin]
  • Nexipride
  • RV-12309
  • S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide
  • S-(-)-Sulpiride
  • UNII-JTG7R315LK

Systematic Names

  • (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • Benzamide, 5-(aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-, (S)- (9CI)
  • o-Anisamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-, (S)-(-)-

Registry Numbers

CAS Registry Number

  • 23672-07-3

FDA UNII

  • JTG7R315LK

System Generated Number

  • 0023672073

Structure Descriptors

InChI

1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1

InChIKey

BGRJTUBHPOOWDU-NSHDSACASA-N

Smiles

CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 170mg/kg (170mg/kg)   European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 437, 1982.
mouse LD50 oral 2450mg/kg (2450mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.
rabbit LD50 intravenous 42mg/kg (42mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.
rabbit LD50 oral > 1500mg/kg (1500mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.
rat LD50 intraperitoneal 270mg/kg (270mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.
rat LD50 intravenous 53mg/kg (53mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.
rat LD50 oral 2600mg/kg (2600mg/kg)   Drugs of the Future. Vol. 12, Pg. 944, 1987.