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Substance Name: Articaine hydrochloride [USAN:USP]
RN: 23964-57-0
UNII: QS9014Q792
InChIKey: GDWDBGSWGNEMGJ-UHFFFAOYSA-N

Note

  • A thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.

Molecular Formula

  • C13-H20-N2-O3-S.Cl-H

Molecular Weight

  • 320.8389
 

Classification Codes

  • Drug / Therapeutic Agent
  • Local Anesthetic
  • Local-Anesthetic
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Names and Synonyms

Name of Substance

  • Articaine hydrochloride [USAN:USP]

Synonyms

  • 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride
  • 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl
  • 40 045
  • Articaine HCl
  • Articaine hydrochloride
  • Carticaine hydrochloride
  • EINECS 245-957-7
  • HOE 045
  • HOE 40045
  • Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride
  • Septanest
  • Ultracain
  • Ultracaine
  • UNII-QS9014Q792

Systematic Names

  • 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride
  • 2-Thiophenecarboxylic acid, 4-methyl-3-(2-(propylamino)propionamido)-, methyl ester, monohydrochloride
  • Methyl 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-2-thenoate monohydrochloride

Registry Numbers

CAS Registry Number

  • 23964-57-0

FDA UNII

  • QS9014Q792

System Generated Number

  • 0023964570

Molecular Formulas

Molecular Formula

  • C13-H20-N2-O3-S.Cl-H

Molecular Formula Fragments

  • C13-H20-N2-O3-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H

InChIKey

GDWDBGSWGNEMGJ-UHFFFAOYSA-N

Smiles

CCCNC(C)C(=O)Nc1c(csc1C(=O)OC)C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 37mg/kg (37mg/kg)   Praktische Anaesthesie, Wiederbelegung und Intensivtherapie. Vol. 9, Pg. 135, 1974.