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Substance Name: Foscolic acid [INN]
RN: 2398-95-0
UNII: DZJ4QTB7YY
InChIKey: RBMHUYBJIYNRLY-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formulas

  • C16-H11-O8-P
  • C6-H11-O8-P

Molecular Weight

  • 242.119
 
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Names and Synonyms

Name of Substance

  • Foscolic acid [INN]

Synonyms

  • 2,2'-Phosphinicobis(2-hydroxypropanoic acid)
  • 2,2'-Phosphinicodilactic acid
  • 4-03-00-01513 (Beilstein Handbook Reference)
  • Acide foscolique
  • Acide foscolique [INN-French]
  • Acido foscolico
  • Acido foscolico [INN-Spanish]
  • Acidum foscolicum
  • Acidum foscolicum [INN-Latin]
  • BRN 1813483
  • Foscolic acid
  • PDLA
  • Phoscolic acid
  • UNII-DZJ4QTB7YY

Systematic Names

  • 2,2'-Phosphinicodilactic acid
  • Lactic acid, 2,2'-phosphinicodi-
  • Propanoic acid, 2,2'-phosphinicobis(2-hydroxy- (9CI)

Registry Numbers

CAS Registry Number

  • 2398-95-0

FDA UNII

  • DZJ4QTB7YY

System Generated Number

  • 0002398950

Structure Descriptors

InChI

1S/C6H11O8P/c1-5(11,3(7)8)15(13,14)6(2,12)4(9)10/h11-12H,1-2H3,(H,7,8)(H,9,10)(H,13,14)

InChIKey

RBMHUYBJIYNRLY-UHFFFAOYSA-N

Smiles

P([C@@](C)(O)C(O)=O)(=O)(O)[C@@](O)(C)C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 260mg/kg (260mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 386, 1964.
mouse LD50 intravenous 152mg/kg (152mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 386, 1964.
mouse LD50 oral 3900mg/kg (3900mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 386, 1964.