Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Flupentixol dihydrochloride
RN: 2413-38-9
UNII: HAT84MLQ6Z
InChIKey: IOVDQEIIMOZNNA-MHKBYHAFSA-N

Note

  • A thioxanthene neuroleptic that, unlike CHLORPROMAZINE, is claimed to have CNS-activating properties. It is used in the treatment of psychoses although not in excited or manic patients. (From Martindale, The Extra Pharmacopoeia, 30th ed, p595)

Molecular Formula

  • C23-H25-F3-N2-O-S.2Cl-H

Molecular Weight

  • 507.4453
 

Classification Code

  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Flupentixol dihydrochloride

Synonyms

  • 1-Piperazineethanol, 4-(3-(2-trifluoromethylthioxanth-9-ylidene)propyl)-, dihydrochloride
  • 4-(3-(2-(Trifluoromethyl)thioxanthen-9-ylidene)propyl)-1-piperazineethanol dihydrochloride
  • EINECS 219-321-4
  • Emergil
  • Flupenthixol, dihydrochloride
  • Flupentixol dihydrochloride
  • Flupentixol HCl
  • Flupentixol hydrochloride
  • FX 703
  • N 7009
  • NSC 170952
  • UNII-HAT84MLQ6Z

Systematic Names

  • 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride (9CI)
  • 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl)-, dihydrochloride (8CI)
  • 4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethanol dihydrochloride
  • Thioxanthene, 9-(3-(4-(2-hydroxyethyl)piperazinyl)propylidene)-2-trifluoromethyl-, dihydrochloride

Registry Numbers

CAS Registry Number

  • 2413-38-9

FDA UNII

  • HAT84MLQ6Z

System Generated Number

  • 0002413389

Molecular Formulas

Molecular Formula

  • C23-H25-F3-N2-O-S.2Cl-H

Molecular Formula Fragments

  • C23-H25-F3-N2-O-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C23H25F3N2OS.2ClH/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29;;/h1-2,4-8,16,29H,3,9-15H2;2*1H/b18-5-;;

InChIKey

IOVDQEIIMOZNNA-MHKBYHAFSA-N

Smiles

c1ccc2c(c1)/C(=C/CCN3CCN(CC3)CCO)/c4cc(ccc4S2)C(F)(F)F.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 94mg/kg (94mg/kg) BEHAVIORAL: SLEEP Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 87, 1962.
mouse LD50 oral 423mg/kg (423mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
mouse LD50 subcutaneous 425mg/kg (425mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
rat LD50 intravenous 37mg/kg (37mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
rat LD50 oral 791mg/kg (791mg/kg)   Drugs in Japan Vol. 6, Pg. 704, 1982.
rat LD50 subcutaneous 258mg/kg (258mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.