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Substance Name: Omalizumab [USAN:INN:BAN]
RN: 242138-07-4
UNII: 2P471X1Z11

Notes

  • A recombinant humanised monoclonal antibody which specifically binds to the C epsilon3 domain of immunoglobulin (Ig) E, the site of high-affinity IgE receptor binding
  • Used to treat atopic diseases, rhinitis and asthma.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Anti-Allergic Agents
  • Anti-Asthmatic Agents
  • Monoclonal Antibody
  • Respiratory System Agents
  • Treatment of Atopic Disease (Asthma; Rhinitis) (Monoclonal Antibody)

Names and Synonyms

Name of Substance

  • Omalizumab
  • Omalizumab [USAN:INN:BAN]

MeSH Heading

  • Omalizumab

Synonyms

  • HSDB 5742
  • HSDB 8176
  • Immunoglobulin G (human-mouse monoclonal E25 clone pSV1E26 gamma-chain anti-human immunoglobulin E Fc region), disulfide with human-mouse monoclonal E25 clone pSVIE126 kappa-chain, dimer. Molecular weight is approximately 150,000 daltons
  • Omalizumab
  • rhuMab-E25
  • UNII-2P471X1Z11
  • Xolair

Systematic Name

  • Immunoglobulin G, anti-(human immunoglobin E FC region) (human-mouse monoclonal E25 clone PSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone PSVIE26 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 242138-07-4

FDA UNII

  • 2P471X1Z11

System Generated Number

  • 0242138074