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Substance Name: Glisolamide [INN]
RN: 24477-37-0
UNII: F83U6T74XR
InChIKey: GZKDXUIWCNCNBJ-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C20-H26-N4-O5-S

Molecular Weight

  • 434.5144
 
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Names and Synonyms

Name of Substance

  • Glisolamide
  • Glisolamide [INN]

Synonyms

  • 1-Cyclohexyl-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)urea
  • BRN 1050609
  • Diabenor
  • Glisolamida
  • Glisolamida [INN-Spanish]
  • Glisolamide
  • Glisolamidum
  • Glisolamidum [INN-Latin]
  • Glysolamide
  • N-(2-(4-((((Cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-3-isoxazolecarboxamide
  • N-(4-(beta-(5-Metilossazol-3-carbossamido)-etil)-benzenesolfonil)-N(sup 1)-cicloesil-urea
  • P.M. 434,526
  • UNII-F83U6T74XR

Systematic Names

  • 1-Cyclohexyl-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)urea
  • 3-Isoxazolecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-
  • 3-Isozazolecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-
  • Urea, 1-cyclohexyl-3-((p-(2-(5-methyl-3-isoxazolecarboxamido)ethyl)phenyl)sulfonyl)-

Registry Numbers

CAS Registry Number

  • 24477-37-0

FDA UNII

  • F83U6T74XR

System Generated Number

  • 0024477370

Structure Descriptors

InChI

1S/C20H26N4O5S/c1-14-13-18(23-29-14)19(25)21-12-11-15-7-9-17(10-8-15)30(27,28)24-20(26)22-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3,(H,21,25)(H2,22,24,26)

InChIKey

GZKDXUIWCNCNBJ-UHFFFAOYSA-N

Smiles

Cc1cc(no1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 230mg/kg (230mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
mouse LD50 oral > 3gm/kg (3000mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
mouse LD50 subcutaneous 720mg/kg (720mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 intraperitoneal 320mg/kg (320mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 oral > 3gm/kg (3000mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.
rat LD50 subcutaneous 900mg/kg (900mg/kg)   Bollettino Chimico Farmaceutico. Vol. 117, Pg. 348, 1978.