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Substance Name: Lenperone hydrochloride
RN: 24677-86-9
UNII: 96Q0TL6O3G
InChIKey: BUPKTBMYUMORNV-UHFFFAOYSA-N

Note

  • Antipsychotic of the butyrophenone class; like other major tranquilizers, it has some alpha-adrenergic blocking action & is antiemetic.

Molecular Formula

  • C22-H23-F2-N-O2.Cl-H

Molecular Weight

  • 407.8856
 

Classification Code

  • Drug / Therapeutic Agent
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Names and Synonyms

Results Name

  • Lenperone hydrochloride

Name of Substance

  • Lenperone hydrochloride

Synonyms

  • 4-(4-(p-Fluorobenzoyl)piperidino)-4'-fluorobutyrophenone hydrochloride
  • AHR 2277
  • Lenperone hydrochloride
  • NSC 303301
  • UNII-96Q0TL6O3G

Systematic Names

  • 1-Butanone, 4-(4-(4-fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)-, hydrochloride (9CI)
  • Butyrophenone, 4'-fluoro-4-(4-(p-fluorobenzoyl)piperidino)-, hydrochloride (8CI)
  • Butyrophenone, 4-(4-(p-fluorobenzoyl)piperidino)-4'-fluoro-, hydrochloride

Registry Numbers

CAS Registry Number

  • 24677-86-9

FDA UNII

  • 96Q0TL6O3G

Related Registry Number

  • 24678-13-5 (Parent)

System Generated Number

  • 0024677869

Molecular Formulas

Molecular Formula

  • C22-H23-F2-N-O2.Cl-H

Molecular Formula Fragments

  • C22-H23-F2-N-O2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C22H23F2NO2.ClH/c23-19-7-3-16(4-8-19)21(26)2-1-13-25-14-11-18(12-15-25)22(27)17-5-9-20(24)10-6-17;/h3-10,18H,1-2,11-15H2;1H

InChIKey

BUPKTBMYUMORNV-UHFFFAOYSA-N

Smiles

c1cc(ccc1C(=O)CCC[NH+]2CCC(CC2)C(=O)c3ccc(cc3)F)F.[Cl-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 50mg/kg (50mg/kg)   Journal of Medicinal Chemistry. Vol. 13, Pg. 1, 1970.
mouse LD50 oral 135mg/kg (135mg/kg)   Journal of Medicinal Chemistry. Vol. 13, Pg. 1, 1970.