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Substance Name: Dermatan sulfate
RN: 24967-94-0

Note

  • A naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue. It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5. (from Merck, 12th ed)

Molecular Formula

  • H2-O4-S.x-Unspecified

Molecular Weight

  • 475.378
 

Classification Codes

  • Anticoagulants
  • Drug / Therapeutic Agent
  • Hematologic Agents
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Links to Resources

Names and Synonyms

Name of Substance

  • Dermatan sulfate

MeSH Heading

  • Dermatan sulfate

Synonyms

  • beta-Heparin
  • Chondroitin sulfate B
  • Chondroitin sulfate type B
  • Chondroitinsulfuric acid
  • Chondroitinsulfuric acid B
  • Chondroitinsulfuric acid type B
  • Chondroitinsulfuric acid, type B
  • Chondroitinsulfuric acids, type B
  • Dermatan 4-sulfate
  • Dermatan hydrogen sulfate
  • Dermatan sulfate, low molecular weight
  • Dermatan sulphate
  • Desmin 370
  • DS 435
  • EINECS 246-552-8
  • MF 701
  • MF 701 (polysaccharide)
  • MF701

Systematic Names

  • Dermatan, 4-(hydrogen sulfate)
  • Dermatan, hydrogen sulfate (ester)

Registry Numbers

CAS Registry Number

  • 24967-94-0

Other Registry Numbers

  • 11120-35-7
  • 11129-22-9
  • 11129-23-0
  • 177697-01-7
  • 42616-56-8
  • 9045-59-4
  • 9083-19-6

System Generated Number

  • 0024967940

Molecular Formulas

Molecular Formula

  • H2-O4-S.x-Unspecified

Molecular Formula Fragments

  • COMPONENT
  • H2-O4-S
  • Unspecified

Structure Descriptors

Smiles

O([C@H]1[C@H]([C@H](O[C@H]([C@@H]1NC(C)=O)O)CO)OS(=O)(=O)[O-])[C@@H]1O[C@H]([C@@H](O)[C@@H]([C@H]1O)O)C(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intravenous > 2gm/kg (2000mg/kg)   Toxicology Letters. Vol. (Suppl), Pg. 245, 1992.
rat LD50 subcutaneous 1660mg/kg (1660mg/kg)   Toxicology Letters. Vol. (Suppl), Pg. 245, 1992.