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Substance Name: Butylated hydroxyanisole [BAN:NF]
RN: 25013-16-5
UNII: REK4960K2U
Note
- Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used as an antioxidant in foods, cosmetics, and pharmaceuticals.
Molecular Formula
- C11-H16-O2
Molecular Weight
- 181.2533
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Antioxidants
- Carcinogens
- Mutation Data
- Noxae
- Pharmaceutic Aid (Antioxidant)
- Protective Agents
- Reproductive Effect
- Tumor Data
Superlist Classification Codes
- Overall Carcinogenic Evaluation: Group 2B
- Reasonably Anticipated to be a Carcinogen
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- (1,1-Dimethylethyl)-4-methoxyphenol
- BHA
- Butylated hydroxyanisole
- Butylated hydroxyanisole [BAN:NF]
- Phenol, (1,1-dimethylethyl)-4-methoxy-
MeSH Heading
- Butylated hydroxyanisole
Synonyms
- (1,1-Dimethylethyl)-4-methoxyphenol
- 2(3)-tert-Butyl-4-hydroxyanisole
- 2-terc.Butyl-4-methoxyfenol
- 2-terc.Butyl-4-methoxyfenol [Czech]
- 3-tert-Butyl-4-hydroxyanisole
- Anisole, butylated hydroxy-
- Antioxyne B
- Antrancine 12
- BHA
- BOA (antioxidant)
- Butyl hydroxyanisole
- Butylated hydroxyanisole
- Butylhydroxyanisole
- Butylohydroksyanizol
- Butylohydroksyanizol [Polish]
- CCRIS 102
- EC 246-563-8
- EEC No. E320
- EINECS 246-563-8
- Embanox
- FEMA No. 2183
- HSDB 3913
- Nepantiox 1-F
- Nipantiox 1-F
- Phenol, (1,1-dimethylethyl)-4-methoxy-
- Phenol, tert-butyl-4-methoxy-
- Protex
- Sustane 1-F
- t-Butyl hydroxyanisole
- Tenox BHA
- tert-Butyl-4-hydroxyanisole
- tert-Butyl-4-methoxyphenol
- UNII-REK4960K2U
Systematic Names
- Butylated hydroxyanisole
- Phenol, (1,1-dimethylethyl)-4-methoxy-
- tert-Butyl-4-methoxyphenol
Superlist Names
- BHA
- Butylated hydroxyanisole
- Phenol, tert-butyl-4-methoxy-
Registry Numbers
CAS Registry Number
- 25013-16-5
FDA UNII
- REK4960K2U
Other Registry Numbers
- 1336-31-8
- 37349-77-2
- 56587-66-7
- 57534-28-8
- 8003-24-5
- 8041-81-4
- 9009-68-1
System Generated Number
- 0025013165
Structure Descriptors
Smiles
[*]C(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 1100mg/kg (1100mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: ATAXIA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970. |
| rabbit | LD50 | oral | 2100mg/kg (2100mg/kg) | Journal of the American Oil Chemists' Society. Vol. 54, Pg. 239, 1977. | |
| rat | LD50 | intraperitoneal | 881mg/kg (881mg/kg) | BLOOD: HEMORRHAGE | Toxicology Letters. Vol. 27, Pg. 15, 1985. |
| rat | LD50 | oral | 2gm/kg (2000mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 51 | deg C | EXP | |
| Boiling Point | 268 | deg C | EXP | |
| log P (octanol-water) | 3.500 | (none) | EST | |
| Water Solubility | 213 | mg/L | 25 | EST |
| Vapor Pressure | 2.48E-03 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.17E-06 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 3.61E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.