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Substance Name: Antazoline hydrochloride [USP]
RN: 2508-72-7
UNII: FP8Q8F72JH
InChIKey: SWKDMSRRIBZZAY-UHFFFAOYSA-N

Molecular Formula

  • C17-H19-N3.Cl-H

Molecular Weight

  • 301.819
 
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Names and Synonyms

Name of Substance

  • Antazoline hydrochloride [USP]

Synonyms

  • 2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride
  • 2-(N-Phenyl-N-benzylaminomethyl)imidazoline hydrochloride
  • 2-Imidazoline, 2-((N-benzylanilino)methyl)-, monohydrochloride
  • 2-Phenylbenzylaminomethylimidazoline hydrochloride
  • Antazoline HCl
  • Antazoline hydrochloride
  • Antazolinium chloratum
  • Antistine hydrochloride
  • EINECS 219-719-8
  • Fenazolina
  • Histazine
  • Phenazoline hydrochloride
  • UNII-FP8Q8F72JH

Systematic Names

  • 2-(N-Benzylanilino)methyl-2-imidazoline, hydrochloride
  • 2-Imidazoline, 2-((N-benzylanilino)methyl)-, hydrochloride
  • Antazoline hydrochloride

Registry Numbers

CAS Registry Number

  • 2508-72-7

FDA UNII

  • FP8Q8F72JH

Related Registry Number

  • 91-75-8 (Parent)

System Generated Number

  • 0002508727

Molecular Formulas

Molecular Formula

  • C17-H19-N3.Cl-H

Molecular Formula Fragments

  • C17-H19-N3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H

InChIKey

SWKDMSRRIBZZAY-UHFFFAOYSA-N

Smiles

c1ccc(cc1)CN(CC2=NCCN2)c3ccccc3.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 30mg/kg (30mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: IRRITABILITY

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 10, Pg. 338, 1951.
guinea pig LD50 intravenous 17100ug/kg (17.1mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 113, Pg. 313, 1958.