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Substance Name: Sincalide [USAN:USP:INN:BAN]
RN: 25126-32-3
UNII: M03GIQ7Z6P
InChIKey: IZTQOLKUZKXIRV-YRVFCXMDSA-N

Note

  • An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.

Molecular Formula

  • C49-H62-N10-O16-S3

Molecular Weight

  • 1143.2808
 

Classification Code

  • Choleretic

Names and Synonyms

Name of Substance

  • Sincalide
  • Sincalide [USAN:USP:INN:BAN]

MeSH Heading

  • Sincalide

Synonyms

  • 1-De(5-oxo-L-proline)-2-de-L-glutamine-5-L-methioninecaerulein
  • EINECS 246-639-0
  • Human CCK-8
  • Kinevac
  • L-alpha-Aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide
  • L-Aspartyl-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-aspartylphenyl-L-alaninamide hydrogen sulfate (ester)
  • Sincalida
  • Sincalida [INN-Spanish]
  • Sincalide
  • Sincalidum
  • Sincalidum [INN-Latin]
  • SQ 19844
  • UNII-M03GIQ7Z6P

Systematic Names

  • Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-5-L-methionine-
  • Sincalide

Registry Numbers

CAS Registry Number

  • 25126-32-3

FDA UNII

  • M03GIQ7Z6P

Other Registry Numbers

  • 25345-10-2
  • 89911-55-7
  • 9038-72-6
  • 91921-74-3

System Generated Number

  • 0025126323

Structure Descriptors

InChI

1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1

InChIKey

IZTQOLKUZKXIRV-YRVFCXMDSA-N

Smiles

CSCC[C@@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc3ccccc3)C(=O)N)NC(=O)[C@H](Cc4ccc(cc4)OS(=O)(=O)O)NC(=O)[C@H](CC(=O)O)N