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Substance Name: Albocycline
RN: 25129-91-3
InChIKey: BYWWNDLILWPPJP-REXWONOSSA-N

Note

  • Macrolide antibiotic isolated from Streptomyces bruneogriseus nov. sp. MCRL-0129; specifically anti-staphylococcal, including antibiotic-resistant strains.

Molecular Formula

  • C18-H28-O4

Molecular Weight

  • 308.415
 
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Names and Synonyms

Name of Substance

  • Albocycline

Synonyms

  • Albocyclin
  • Cineromycin-B-methylaether
  • Ingramycin
  • TA-2407

Systematic Name

  • Albocycline

Registry Numbers

CAS Registry Number

  • 25129-91-3

System Generated Number

  • 0025129913

Structure Descriptors

InChI

1S/C18H28O4/c1-13-7-6-8-14(2)16(21-5)9-11-18(4,20)12-10-17(19)22-15(13)3/h8-13,15-16,20H,6-7H2,1-5H3/b11-9+,12-10+,14-8+/t13-,15+,16-,18+/m0/s1

InChIKey

BYWWNDLILWPPJP-REXWONOSSA-N

Smiles

C1(C=C[C@@](C=C[C@H](OC)C(C)=CCC[C@@H]([C@H](O1)C)C)(O)C)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 intraperitoneal 1gm/kg (1000mg/kg)   Hindustan Antibiotics Bulletin. Vol. 11, Pg. 26, 1969.
mouse LD50 intraperitoneal 1500mg/kg (1500mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 2, Pg. 374, 1980.