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Substance Name: Etofamide [INN]
RN: 25287-60-9
UNII: 03F36JH21U
InChIKey: QTRALMGDQMIVFF-UHFFFAOYSA-N

Classification Codes

  • Amebicides
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Antiprotozoal Agents
  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H20-Cl2-N2-O5

Molecular Weight

  • 427.282
 
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Names and Synonyms

Name of Substance

  • Etofamide
  • Etofamide [INN]

Synonyms

  • 2,2-Dichloro-N-(2-ethoxyethyl)-N-((p-nitrophenoxy)benzyl)-acetamide
  • 2,2-Dichloro-N-(2-ethoxyethyl)-N-(p-(p-nitrophenoxy)benzyl)acetamide
  • 4-13-00-01742 (Beilstein Handbook Reference)
  • BRN 2918322
  • Chlorophenoxamide ethyl ether
  • EINECS 246-790-2
  • Ethylchlordiphene
  • Eticlordifene
  • Etofamida
  • Etofamida [INN-Spanish]
  • Etofamide
  • Etofamidum
  • Etofamidum [INN-Latin]
  • K-430
  • Kitnos
  • Kitnosil
  • N-(2-Etossietil)-N-(4-(4'-nitrofenossi)benzil)dicloroacetamide
  • N-(2-Etossietil)-N-(4-(4'-nitrofenossi)benzil)dicloroacetamide [Italian]
  • UNII-03F36JH21U

Systematic Names

  • 2,2-Dichloro-N-(2-ethoxyethyl)-N-((p-nitrophenoxy)benzyl)-acetamide
  • Acetamide, 2,2-dichloro-N-(2-ethoxyethyl)-N-((4-(4-nitrophenoxy)phenyl)methyl)- (9CI)
  • Acetamide, 2,2-dichloro-N-(2-ethoxyethyl)-N-(p-(p-nitrophenoxy)benzyl)-
  • Etofamide
  • N-(2-Ethoxyethyl)-N-(p-(p-nitrophenoxy)-benzyl)dichloracetamide

Registry Numbers

CAS Registry Number

  • 25287-60-9

FDA UNII

  • 03F36JH21U

System Generated Number

  • 0025287609

Structure Descriptors

InChI

1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3

InChIKey

QTRALMGDQMIVFF-UHFFFAOYSA-N

Smiles

c1(ccc(Oc2ccc(cc2)[N+](=O)[O-])cc1)CN(C(C(Cl)Cl)=O)CCOCC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD intraperitoneal > 5gm/kg (5000mg/kg)   Farmaco, Edizione Pratica. Vol. 27, Pg. 585, 1972.
mouse LD oral > 5gm/kg (5000mg/kg)   Farmaco, Edizione Pratica. Vol. 27, Pg. 585, 1972.
rat LD50 intraperitoneal 2gm/kg (2000mg/kg)   Giornale di Malattie Infettive e Parassitarie. Journal of Infectious and Parasitic Diseases. Vol. 10, Pg. 850, 1958.
rat LD50 oral > 5gm/kg (5000mg/kg)   Giornale di Malattie Infettive e Parassitarie. Journal of Infectious and Parasitic Diseases. Vol. 10, Pg. 850, 1958.