Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tyloxapol [USAN:USP:INN:BAN]
RN: 25301-02-4
UNII: Y27PUL9H56

Note

  • Non-ionic detergent with surface-active properties; incompatible with metals; surfactant also used in inhalation therapy; N1 is from CA Vol 90 Form Index.

Molecular Formula

  • (C14-H22-O.C2-H4-O.C-H2-O)x-

Molecular Weight

  • 280.405
 

Classification Codes

  • Detergent
  • Detergents
  • Drug / Therapeutic Agent
  • Reproductive Effect
  • Surface-Active Agents
* denotes mobile formatted website

Links to Resources

Names and Synonyms

Name of Substance

  • Tyloxapol
  • Tyloxapol [USAN:USP:INN:BAN]

Synonyms

  • Alevaire
  • Ethylene oxide-formaldehyde-p-octylphenol copolymer
  • Macrocyclon
  • NSC 90255
  • Oxyethylated tertiary octyl-phenol-formaldehyde polymer
  • p-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde
  • p-Isooctylpolyoxyethylenephenol formaldehyde polymer
  • Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane
  • Superinone
  • Tiloxapol
  • Tiloxapol [INN-Spanish]
  • Triton A-20
  • Triton W.R.1339
  • Triton WR 1339
  • Tyloxapol
  • Tyloxapolum
  • Tyloxapolum [INN-Latin]
  • UNII-Y27PUL9H56

Systematic Names

  • 4-(1,1,3,3-Tetramethylbutyl)phenol, polymer with formaldehyde & oxirane
  • Formaldehyde, polymer with oxirane and 4-(1,1,3,3-tetramethylbutyl)phenol
  • Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane
  • Phenol, p-(1,1,3,3-tetramethylbutyl)-, polymer with ethylene oxide and formaldehyde

Mixture Names

  • Enuclene
  • Exosurf

Registry Numbers

CAS Registry Number

  • 25301-02-4

FDA UNII

  • Y27PUL9H56

Other Registry Numbers

  • 9014-50-0
  • 9014-66-8
  • 9015-10-5

System Generated Number

  • 0025301024

Molecular Formulas

Molecular Formula

  • (C14-H22-O.C2-H4-O.C-H2-O)x-

Molecular Formula Fragments

  • C-H2-O
  • C14-H22-O
  • C2-H4-O
  • COMPONENT

Structure Descriptors

Smiles

Oc1ccc(C(C)(C)CC(C)(C)C)cc1.C1CO1.C=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
mouse LD50 intravenous > 3800mg/kg (3800mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
rat LD50 intravenous 1800mg/kg (1800mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 467, 1982.