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Substance Name: Macrogol [INN]
RN: 25322-68-3
Notes
- A tasteless laxative composed of PEG3350; Miralax is tradename.
- Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.
Molecular Formula
- (C2-H4-O)mult-H2-O
Molecular Weight
- 44.0526
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Drug / Therapeutic Agent
- Excipients
- Mutation Data
- Pharmaceutic Aid (Ointment Base)
- Pharmaceutic Aid (Solvent)
- Pharmaceutic Aid (Suppository Base)
- Pharmaceutic Aid (Suspending and/or Viscosity Agent)
- Pharmaceutic Aid (Tablet and/or Capsule Lubricant)
- Pharmaceutic Aid (Tablet Binder)
- Pharmaceutic Aid (Tablet Excipient)
- Pharmaceutic Aids
- Pharmaceutical Vehicles
- Skin / Eye Irritant
- Solvents
- Surface-Active Agents
- TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
- Tumor Data
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Results Name
- Macrogol [INN]
Name of Substance
- Ethanol, 2,2'-(oxybis(2,1-ethanediyloxy)bis-
- Macrogol [INN]
- Polyethylene glycol
- Polyethylene glycol 1000
- Polyethylene glycol 1450
- Polyethylene glycol 1500
- Polyethylene glycol 1540
- Polyethylene glycol 200
- Polyethylene glycol 300
- Polyethylene glycol 3350
- Polyethylene glycol 3500
- Polyethylene glycol 400
- Polyethylene glycol 4000
- Polyethylene glycol 4500
- Polyethylene glycol 7000
- Polyethylene glycol 800
- Polyethylene glycol 8000
- Polyethylene glycol 900
- Polyethylene glycol [NF]
- Polyox wsr-N 60
MeSH Heading
- Polyethylene Glycols
Synonyms
- 1,2-Ethanediol homopolymer
- Alcox E 30
- Alkox E 100
- Alkox E 130
- Alkox E 160
- Alkox E 240
- Alkox E 45
- Alkox E 60
- Alkox E 75
- Alkox R 1000
- Alkox R 15
- Alkox R 150
- Alkox R 400
- Alkox SR
- alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
- alpha-Hydro-omega-hydroxypoly(oxyethylene)
- Antarox E 4000
- Aquacide III
- Aquaffin
- Atpeg 300
- Atpeg 4000
- Badimol
- BDH 301
- Bradsyn PEG
- Breox 2000
- Breox 20M
- Breox 4000
- Breox 550
- Breox PEG 300
- CAFO 154
- Carbowax
- Carbowax 100
- Carbowax 1000
- Carbowax 1350
- Carbowax 14000
- Carbowax 1500
- Carbowax 1540
- Carbowax 20
- Carbowax 200
- Carbowax 20000
- Carbowax 25000
- Carbowax 300
- Carbowax 3350
- Carbowax 400
- Carbowax 4000
- Carbowax 4500
- Carbowax 4600
- Carbowax 600
- Carbowax 8000
- Carbowax Sentry
- CCRIS 979
- Clearlax
- DD 3002
- Deactivator H
- EC 500-038-2
- EINECS 266-688-1
- Emkapol 4200
- Ethoxylated 1,2-ethanediol
- Ethylene glycol homopolymer
- Ethylene glycol polymer
- Forlax
- Gafanol E 200
- Gavilax
- Glycols, polyethylene
- HM 500
- HSDB 5159
- Lutrol
- Lutrol E
- Macrogol
- Macrogol 3350
- Merpol OJ
- Miralax
- Modopeg
- Nosilen
- NSC 152324
- Nycoline
- Oxide Wax AN
- Oxyethylene polymer
- PEG
- PEG 1000
- PEG 1500
- PEG 1540
- PEG 200
- PEG 300
- PEG 3350
- PEG 3500
- PEG 400
- PEG 4000
- PEG 4500
- PEG 6000DS
- PEG 800
- PEG 8o00
- PEG 900
- PEG-1000
- PEG-1500
- PEG-1540
- PEG-200
- PEG-300
- PEG-3350
- PEG-3500
- PEG-4000
- PEG-4500
- PEG-800
- PEG-8000
- PEG-900
- Plenvu
- Pluracol E
- Pluracol E 400, E 600, E 1450
- Pluriol E 200
- Poly(oxy-1,2-ethanediyl, alpha-hydro-omega-hydroxy-
- Poly-G
- Poly-G600
- Polyethylene glycol
- Polyethylene glycol 1000
- Polyethylene glycol 1450
- Polyethylene glycol 1500
- Polyethylene glycol 1540
- Polyethylene glycol 200
- Polyethylene glycol 300
- Polyethylene glycol 3350
- Polyethylene glycol 3500
- Polyethylene glycol 400
- Polyethylene glycol 4000
- Polyethylene glycol 4500
- Polyethylene glycol 6000
- Polyethylene glycol 7000
- Polyethylene glycol 800
- Polyethylene glycol 8000
- Polyethylene glycol 900
- Polyethylene oxide
- Polyglycol E 300, E 400, E 1450, E 8000
- Polyoxyethylene ether
- Sentry polyox WSR
- UNII-11628IH70O
- UNII-1212Z7S33A
- UNII-16P9295IIL
- UNII-2126FD486L
- UNII-2L7WA456VA
- UNII-30IQX730WE
- UNII-3H4G04L531
- UNII-3IG9032SAH
- UNII-3WJQ0SDW1A
- UNII-439X29GCJZ
- UNII-4QIB4U4CQR
- UNII-4R4HFI6D95
- UNII-5246R0812J
- UNII-5655G9Y8AQ
- UNII-5IRA46LB71
- UNII-5K3991GVWI
- UNII-5WKN5KL2O8
- UNII-74D3A2BP47
- UNII-761NX2Q08Y
- UNII-762678AC5R
- UNII-77HY82S0LG
- UNII-7Z3ER739EB
- UNII-8EIY1IHX76
- UNII-9XH9HVO466
- UNII-B697894SGQ
- UNII-FVS1AZD90Y
- UNII-G2M7P15E5P
- UNII-G3MS6M810Y
- UNII-H57W405143
- UNII-HAF0412YIT
- UNII-HZ58M6D839
- UNII-NL4J9F21N9
- UNII-OJ4Z5Z32L4
- UNII-Q0JET65GEL
- UNII-Q662QK8M3B
- UNII-R0XY39567G
- UNII-RU64142H6P
- UNII-RVV61677RZ
- UNII-SA1B764746
- UNII-TU0XPZ7FZT
- UNII-TVH7653921
- UNII-U076Q6Q621
- UNII-U95VVU3IDQ
- UNII-UEP843BRCQ
- UNII-UH6KR4953D
- UNII-V146K8QJ07
- UNII-V46Y6OJ5QB
- UNII-VM53EE110J
- UNII-X83H03O8BZ
- UNII-Y4QO2MSY3X
- UNII-ZBR3T82M2V
Systematic Names
- Glycols, polyethylene (8CI)
- Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-
- Poly(oxy-1,2-ethanediyl),alpha-hydro-omega-hydroxy- ethane-1,2-diol, ethoxylated
- Polyethylene glycol
- WSR-301
Superlist Names
- Glycols, polyethylene
- PEG
- Polyethylene glycol
Mixture Name
- Colyte
Registry Numbers
CAS Registry Number
- 25322-68-3
FDA UNIIs
- 11628IH70O
- 1212Z7S33A
- 16P9295IIL
- 2126FD486L
- 2L7WA456VA
- 30IQX730WE
- 3H4G04L531
- 3IG9032SAH
- 3WJQ0SDW1A
- 439X29GCJZ
- 4QIB4U4CQR
- 4R4HFI6D95
- 5246R0812J
- 5655G9Y8AQ
- 5IRA46LB71
- 5K3991GVWI
- 5WKN5KL2O8
- 74D3A2BP47
- 761NX2Q08Y
- 762678AC5R
- 77HY82S0LG
- 7Z3ER739EB
- 8EIY1IHX76
- 9XH9HVO466
- B697894SGQ
- FVS1AZD90Y
- G2M7P15E5P
- G3MS6M810Y
- H57W405143
- HAF0412YIT
- HZ58M6D839
- NL4J9F21N9
- OJ4Z5Z32L4
- Q0JET65GEL
- Q662QK8M3B
- R0XY39567G
- RU64142H6P
- RVV61677RZ
- SA1B764746
- TU0XPZ7FZT
- TVH7653921
- U076Q6Q621
- U95VVU3IDQ
- UEP843BRCQ
- UH6KR4953D
- V146K8QJ07
- V46Y6OJ5QB
- VM53EE110J
- X83H03O8BZ
- Y4QO2MSY3X
- ZBR3T82M2V
Other Registry Numbers
- 1011711-38-8
- 101677-86-5
- 1033001-32-9
- 1035554-64-3
- 106186-24-7
- 107502-63-6
- 107529-96-4
- 109550-27-8
- 112384-37-9
- 112895-21-3
- 113041-64-8
- 114323-93-2
- 1152430-37-9
- 116549-90-7
- 1186292-40-9
- 1186292-41-0
- 119219-06-6
- 1204298-97-4
- 1221382-78-0
- 1221382-83-7
- 1221889-65-1
- 1246265-64-4
- 125223-68-9
- 1256377-90-8
- 1267533-36-7
- 12676-74-3
- 12770-93-3
- 1287768-38-0
- 1293291-01-6
- 1319730-68-1
- 1330618-78-4
- 133573-31-6
- 1338951-32-8
- 134919-43-0
- 1373256-89-3
- 1377964-82-3
- 1422717-42-7
- 1429745-88-9
- 1434253-80-1
- 1435263-27-6
- 1446681-77-1
- 1474108-09-2
- 150872-82-5
- 154394-38-4
- 156948-19-5
- 1613520-06-1
- 1620693-21-1
- 1628723-15-8
- 1636129-20-8
- 169046-53-1
- 1696472-65-7
- 1710469-72-9
- 174460-08-3
- 174460-09-4
- 1800416-42-5
- 1809027-71-1
- 1852508-98-5
- 1873338-22-7
- 188364-77-4
- 188924-03-0
- 189154-62-9
- 191743-71-2
- 1927875-70-4
- 196696-84-1
- 201163-43-1
- 2015216-86-9
- 206357-86-0
- 2088235-52-1
- 2092889-80-8
- 2122851-44-7
- 2170314-63-1
- 221638-71-7
- 225502-44-3
- 25104-58-9
- 25609-81-8
- 270910-26-4
- 307928-07-0
- 34802-42-1
- 356055-70-4
- 37361-15-2
- 391229-98-4
- 402483-26-5
- 411207-22-2
- 497171-83-2
- 50809-04-6
- 50809-59-1
- 51312-32-4
- 54510-95-1
- 54847-64-2
- 59763-40-5
- 60894-12-4
- 615575-04-7
- 61840-14-0
- 64441-68-5
- 64640-28-4
- 67411-64-7
- 6790-09-6
- 70926-57-7
- 75285-02-8
- 75285-03-9
- 77986-38-0
- 79964-26-4
- 80341-53-3
- 8038-37-7
- 85399-22-0
- 857367-46-5
- 859315-72-3
- 85945-29-5
- 863328-36-3
- 876655-84-4
- 88077-80-9
- 886469-28-9
- 88747-22-2
- 90597-70-9
- 9081-95-2
- 9085-02-3
- 9085-03-4
- 952682-62-1
- 956217-69-9
- 959127-49-2
- 99264-61-6
- 99333-89-8
System Generated Number
- 0025322683
Molecular Formulas
Molecular Formula
- (C2-H4-O)mult-H2-O
Molecular Formula Fragments
- C2-H4-O
- COMPONENT
- H2-O
Structure Descriptors
Smiles
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 3gm/kg (3000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. | |
| guinea pig | LD50 | oral | 15700mg/kg (15700mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 17gm/kg (17000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| guinea pig | LD50 | oral | 19600mg/kg (19600mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 22500mg/kg (22500mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| guinea pig | LD50 | oral | 28gm/kg (28000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| guinea pig | LD50 | oral | 28900mg/kg (28900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 50gm/kg (50000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 50900mg/kg (50900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| mouse | LD50 | intraperitoneal | 473mg/kg (473mg/kg) | Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 21, Pg. 387, 1986. | |
| mouse | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. |
| mouse | LD50 | intraperitoneal | 7500mg/kg (7500mg/kg) | National Technical Information Service. Vol. AD628-313, | |
| mouse | LD50 | intraperitoneal | 8gm/kg (8000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. |
| mouse | LD50 | intravenous | 7900ug/kg (7.9mg/kg) | Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 316, 1970. | |
| mouse | LD50 | intravenous | 8550mg/kg (8550mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| mouse | LD50 | intravenous | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| mouse | LD50 | oral | 28915mg/kg (28915mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| mouse | LD50 | oral | 31gm/kg (31000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | oral | 34gm/kg (34000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | oral | 36gm/kg (36000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | subcutaneous | 18gm/kg (18000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD | skin | > 1gm/kg (1000mg/kg) | Union Carbide Data Sheet. Vol. 9/25/1969, | |
| rabbit | LD50 | intravenous | 8gm/kg (8000mg/kg) | BLOOD: CHANGE IN CLOTTING FACTORS | Kriobiologiya i Kriomeditsina. Cryobiology and Cryomedicine. Vol. 4, Pg. 71, 1978. |
| rabbit | LD50 | oral | 14gm/kg (14000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rabbit | LD50 | oral | 17300mg/kg (17300mg/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | oral | 17300mg/kg (17300mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 19gm/kg (19000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rabbit | LD50 | oral | 26800mg/kg (26800mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 28900mg/kg (28900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 76gm/kg (76000mg/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | oral | 76gm/kg (76000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | skin | > 20mL/kg (20mL/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-1112, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2202, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-96, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2203, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-937, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-939, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-935, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-940, | |
| rat | LD | oral | > 4gm/kg (4000mg/kg) | Union Carbide Data Sheet. Vol. 9/25/1969, | |
| rat | LD50 | intraperitoneal | 6790mg/kg (6790mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 9gm/kg (9000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 9700mg/kg (9700mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intraperitoneal | 9708mg/kg (9708mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| rat | LD50 | intraperitoneal | 12600mg/kg (12600mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 14100mg/kg (14100mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intraperitoneal | 15390mg/kg (15390mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 15570mg/kg (15570mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 17gm/kg (17000mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| rat | LD50 | intraperitoneal | 17700mg/kg (17700mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intravenous | 7130mg/kg (7130mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intravenous | 7312mg/kg (7312mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| rat | LD50 | intravenous | 7500mg/kg (7500mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intravenous | 13gm/kg (13000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 600mg/kg (600mg/kg) | Dow Chemical Company Reports. Vol. MSD-94, | |
| rat | LD50 | oral | 1054mg/kg (1054mg/kg) | Dow Chemical Company Reports. Vol. MSD-95, | |
| rat | LD50 | oral | > 4gm/kg (4000mg/kg) | Dow Chemical Company Reports. Vol. MSD-938, | |
| rat | LD50 | oral | 22gm/kg (22000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | 27500mg/kg (27500mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 28gm/kg (28000mg/kg) | Dow Chemical Company Reports. Vol. MSD-1112, | |
| rat | LD50 | oral | 30gm/kg (30000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2203, | |
| rat | LD50 | oral | 30200mg/kg (30200mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| rat | LD50 | oral | 31600mg/kg (31600mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | 31640mg/kg (31640mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 32gm/kg (32000mg/kg) | Dow Chemical Company Reports. Vol. MSD-937, | |
| rat | LD50 | oral | 44200mg/kg (44200mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 45gm/kg (45000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | > 50gm/kg (50000mg/kg) | Dow Chemical Company Reports. Vol. MSD-935, | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | > 50gm/kg (50000mg/kg) | Dow Chemical Company Reports. Vol. MSD-940, | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 51200mg/kg (51200mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 51310mg/kg (51310mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | subcutaneous | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | unreported | 7800mg/kg (7800mg/kg) | United States Patent Document. Vol. #4767763, | |
| rat | LDLo | intravenous | 3mg/kg (3mg/kg) | Toxicology and Applied Pharmacology. Vol. 16, Pg. 442, 1970. | |
| rat | LDLo | intravenous | 22gm/kg (22000mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1087, 1973. |