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Substance Name: Macrogol [INN]
RN: 25322-68-3
Notes
- A tasteless laxative composed of PEG3350; Miralax is tradename.
- Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.
- Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.
Molecular Formulas
- (C2-H4-O)mult-
- (C2-H4-O)mult-H2-O
Molecular Weight
- 44.0526
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Drug / Therapeutic Agent
- Drug Carriers
- Excipients
- Gastrointestinal Agents
- Laxatives
- Mutation Data
- Pharmaceutic Aid (Ointment Base)
- Pharmaceutic Aid (Solvent)
- Pharmaceutic Aid (Suppository Base)
- Pharmaceutic Aid (Suspending and/or Viscosity Agent)
- Pharmaceutic Aid (Tablet and/or Capsule Lubricant)
- Pharmaceutic Aid (Tablet Binder)
- Pharmaceutic Aid (Tablet Excipient)
- Pharmaceutic Aids
- Pharmaceutical Vehicles
- Skin / Eye Irritant
- Solvents
- Surface-Active Agents
- TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
- Tumor Data
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Results Name
- Macrogol [INN]
Name of Substance
- Ethanol, 2,2'-(oxybis(2,1-ethanediyloxy)bis-
- Macrogol [BAN:JAN]
- Macrogol [INN]
- Polyethylene glycol
- Polyethylene glycol 1000
- Polyethylene glycol 1450
- Polyethylene glycol 1500
- Polyethylene glycol 1540
- Polyethylene glycol 200
- Polyethylene glycol 2000
- Polyethylene glycol 300
- Polyethylene glycol 3350
- Polyethylene glycol 3500
- Polyethylene glycol 400
- Polyethylene glycol 4000
- Polyethylene glycol 4500
- Polyethylene glycol 7000
- Polyethylene glycol 800
- Polyethylene glycol 8000
- Polyethylene glycol 900
- Polyethylene glycol [NF]
- Polyox wsr-N 60
MeSH Heading
- Polyethylene Glycols
Synonyms
- 1,2-Ethanediol homopolymer
- Alcox E 30
- Alkox E 100
- Alkox E 130
- Alkox E 160
- Alkox E 240
- Alkox E 45
- Alkox E 60
- Alkox E 75
- Alkox R 1000
- Alkox R 15
- Alkox R 150
- Alkox R 400
- Alkox SR
- alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
- alpha-Hydro-omega-hydroxypoly(oxyethylene)
- Antarox E 4000
- Aquacide III
- Aquaffin
- Atpeg 300
- Atpeg 4000
- Badimol
- BDH 301
- Bradsyn PEG
- Breox 2000
- Breox 20M
- Breox 4000
- Breox 550
- Breox PEG 300
- CAFO 154
- Carbowax
- Carbowax 100
- Carbowax 1000
- Carbowax 1350
- Carbowax 14000
- Carbowax 1500
- Carbowax 1540
- Carbowax 20
- Carbowax 200
- Carbowax 20000
- Carbowax 25000
- Carbowax 300
- Carbowax 3350
- Carbowax 400
- Carbowax 4000
- Carbowax 4500
- Carbowax 4600
- Carbowax 600
- Carbowax 8000
- Carbowax Sentry
- CCRIS 979
- Clearlax
- DD 3002
- Deactivator H
- EC 500-038-2
- EINECS 266-688-1
- Emkapol 4200
- Ethoxylated 1,2-ethanediol
- Ethylene glycol homopolymer
- Ethylene glycol polymer
- Forlax
- Gafanol E 200
- Gavilax
- Glycols, polyethylene
- HM 500
- HSDB 5159
- Lanogene C
- Lutrol
- Lutrol E
- Macrogol
- Macrogol 300
- Macrogol 3350
- Macrogol 6000
- Merpol OJ
- Miralax
- Modopeg
- Nosilen
- NSC 152324
- Nycoline
- Oxide Wax AN
- Oxyethylene polymer
- PEG
- PEG 1000
- PEG 1500
- PEG 1540
- PEG 200
- PEG 300
- PEG 3350
- PEG 3500
- PEG 400
- PEG 4000
- PEG 4500
- PEG 6000
- PEG 6000DS
- PEG 800
- PEG 8000
- PEG 8o00
- PEG 900
- PEG-1000
- PEG-1500
- PEG-1540
- PEG-200
- PEG-300
- PEG-3350
- PEG-3500
- PEG-400
- PEG-4000
- PEG-4500
- PEG-800
- PEG-8000
- PEG-900
- PEO-400
- Plenvu
- Pluracol E
- Pluracol E 400, E 600, E 1450
- Pluriol E 200
- Poly(oxy-1,2-ethanediyl)
- Poly(oxy-1,2-ethanediyl, alpha-hydro-omega-hydroxy-
- Poly-G
- Poly-G600
- Polyethylene glycol
- Polyethylene glycol 1000
- Polyethylene glycol 1450
- Polyethylene glycol 1500
- Polyethylene glycol 1540
- Polyethylene glycol 200
- Polyethylene glycol 300
- Polyethylene glycol 3350
- Polyethylene glycol 3500
- Polyethylene glycol 400
- Polyethylene glycol 4000
- Polyethylene glycol 4500
- Polyethylene glycol 6000
- Polyethylene glycol 7000
- Polyethylene glycol 800
- Polyethylene glycol 8000
- Polyethylene glycol 900
- Polyethylene oxide
- Polyglycol E 300, E 400, E 1450, E 8000
- Polyox WSR N-60K
- Polyoxyethylene ether
- Sentry polyox WSR
- Sulfate-free electrolyte lavage solution
- UNII-11628IH70O
- UNII-1212Z7S33A
- UNII-16P9295IIL
- UNII-2126FD486L
- UNII-2L7WA456VA
- UNII-30IQX730WE
- UNII-3H4G04L531
- UNII-3IG9032SAH
- UNII-3WJQ0SDW1A
- UNII-439X29GCJZ
- UNII-4QIB4U4CQR
- UNII-4R4HFI6D95
- UNII-5246R0812J
- UNII-5655G9Y8AQ
- UNII-5IRA46LB71
- UNII-5K3991GVWI
- UNII-5WKN5KL2O8
- UNII-74D3A2BP47
- UNII-761NX2Q08Y
- UNII-762678AC5R
- UNII-77HY82S0LG
- UNII-7Z3ER739EB
- UNII-8EIY1IHX76
- UNII-9XH9HVO466
- UNII-B697894SGQ
- UNII-FVS1AZD90Y
- UNII-G2M7P15E5P
- UNII-G3MS6M810Y
- UNII-H57W405143
- UNII-HAF0412YIT
- UNII-HZ58M6D839
- UNII-NL4J9F21N9
- UNII-OJ4Z5Z32L4
- UNII-Q0JET65GEL
- UNII-Q662QK8M3B
- UNII-R0XY39567G
- UNII-RU64142H6P
- UNII-RVV61677RZ
- UNII-SA1B764746
- UNII-TU0XPZ7FZT
- UNII-TVH7653921
- UNII-U076Q6Q621
- UNII-U95VVU3IDQ
- UNII-UEP843BRCQ
- UNII-UH6KR4953D
- UNII-V146K8QJ07
- UNII-V46Y6OJ5QB
- UNII-VM53EE110J
- UNII-X83H03O8BZ
- UNII-Y4QO2MSY3X
- UNII-ZBR3T82M2V
Systematic Names
- Glycols, polyethylene (8CI)
- Poly(oxy-1,2-ethanediyl)
- Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-
- Poly(oxy-1,2-ethanediyl),alpha-hydro-omega-hydroxy- ethane-1,2-diol, ethoxylated
- Polyethylene glycol
- WSR-301
Superlist Names
- Ethylene oxide polymer
- Glycols, polyethylene
- PEG
- Polyethylene glycol
Mixture Name
- Colyte
Registry Numbers
CAS Registry Number
- 25322-68-3
FDA UNIIs
- 11628IH70O
- 1212Z7S33A
- 16P9295IIL
- 2126FD486L
- 2L7WA456VA
- 30IQX730WE
- 3H4G04L531
- 3IG9032SAH
- 3WJQ0SDW1A
- 439X29GCJZ
- 4QIB4U4CQR
- 4R4HFI6D95
- 5246R0812J
- 5655G9Y8AQ
- 5IRA46LB71
- 5K3991GVWI
- 5WKN5KL2O8
- 74D3A2BP47
- 761NX2Q08Y
- 762678AC5R
- 77HY82S0LG
- 7Z3ER739EB
- 8EIY1IHX76
- 9XH9HVO466
- B697894SGQ
- FVS1AZD90Y
- G2M7P15E5P
- G3MS6M810Y
- H57W405143
- HAF0412YIT
- HZ58M6D839
- NL4J9F21N9
- OJ4Z5Z32L4
- Q0JET65GEL
- Q662QK8M3B
- R0XY39567G
- RU64142H6P
- RVV61677RZ
- SA1B764746
- TU0XPZ7FZT
- TVH7653921
- U076Q6Q621
- U95VVU3IDQ
- UEP843BRCQ
- UH6KR4953D
- V146K8QJ07
- V46Y6OJ5QB
- VM53EE110J
- X83H03O8BZ
- Y4QO2MSY3X
- ZBR3T82M2V
Other Registry Numbers
- 1011711-38-8
- 101677-86-5
- 1033001-32-9
- 1035554-64-3
- 106186-24-7
- 107502-63-6
- 107529-96-4
- 109550-27-8
- 112384-37-9
- 112895-21-3
- 113041-64-8
- 114323-93-2
- 1152430-37-9
- 116549-90-7
- 1186292-40-9
- 1186292-41-0
- 119219-06-6
- 1204298-97-4
- 1221382-78-0
- 1221382-83-7
- 1221889-65-1
- 1246265-64-4
- 125223-68-9
- 1256377-90-8
- 1267533-36-7
- 12676-74-3
- 12770-93-3
- 1287768-38-0
- 1293291-01-6
- 1319730-68-1
- 1330618-78-4
- 133573-31-6
- 1338951-32-8
- 134919-43-0
- 1373256-89-3
- 1377964-82-3
- 1422717-42-7
- 1429745-88-9
- 1434253-80-1
- 1435263-27-6
- 1446681-77-1
- 1474108-09-2
- 150872-82-5
- 154394-38-4
- 156948-19-5
- 1613520-06-1
- 1620693-21-1
- 1628723-15-8
- 1636129-20-8
- 169046-53-1
- 1696472-65-7
- 1710469-72-9
- 174460-08-3
- 174460-09-4
- 1800416-42-5
- 1809027-71-1
- 1852508-98-5
- 1873338-22-7
- 188364-77-4
- 188924-03-0
- 189154-62-9
- 191743-71-2
- 1927875-70-4
- 196696-84-1
- 201163-43-1
- 2015216-86-9
- 206357-86-0
- 2088235-52-1
- 2092889-80-8
- 2122851-44-7
- 2170314-63-1
- 221638-71-7
- 225502-44-3
- 25104-58-9
- 25609-81-8
- 270910-26-4
- 307928-07-0
- 34802-42-1
- 356055-70-4
- 37361-15-2
- 391229-98-4
- 402483-26-5
- 411207-22-2
- 497171-83-2
- 50809-04-6
- 50809-59-1
- 51312-32-4
- 54510-95-1
- 54847-64-2
- 59763-40-5
- 60894-12-4
- 615575-04-7
- 61840-14-0
- 64441-68-5
- 64640-28-4
- 67411-64-7
- 6790-09-6
- 70926-57-7
- 75285-02-8
- 75285-03-9
- 77986-38-0
- 79964-26-4
- 80341-53-3
- 8038-37-7
- 85399-22-0
- 857367-46-5
- 859315-72-3
- 85945-29-5
- 863328-36-3
- 876655-84-4
- 88077-80-9
- 886469-28-9
- 88747-22-2
- 9002-90-8
- 90597-70-9
- 9081-95-2
- 9085-02-3
- 9085-03-4
- 952682-62-1
- 956217-69-9
- 959127-49-2
- 99264-61-6
- 99333-89-8
System Generated Number
- 0025322683
Molecular Formulas
Molecular Formulas
- (C2-H4-O)mult-
- (C2-H4-O)mult-H2-O
Molecular Formula Fragments
- C2-H4-O
- COMPONENT
- H2-O
Structure Descriptors
Smiles
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 3gm/kg (3000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. | |
| guinea pig | LD50 | oral | 15700mg/kg (15700mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 17gm/kg (17000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| guinea pig | LD50 | oral | 19600mg/kg (19600mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 22500mg/kg (22500mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| guinea pig | LD50 | oral | 28gm/kg (28000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| guinea pig | LD50 | oral | 28900mg/kg (28900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 50gm/kg (50000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| guinea pig | LD50 | oral | 50900mg/kg (50900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| mouse | LD50 | intraperitoneal | 473mg/kg (473mg/kg) | Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 21, Pg. 387, 1986. | |
| mouse | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. |
| mouse | LD50 | intraperitoneal | 7500mg/kg (7500mg/kg) | National Technical Information Service. Vol. AD628-313, | |
| mouse | LD50 | intraperitoneal | 8gm/kg (8000mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951. |
| mouse | LD50 | intravenous | 7900ug/kg (7.9mg/kg) | Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 316, 1970. | |
| mouse | LD50 | intravenous | 8550mg/kg (8550mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| mouse | LD50 | intravenous | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| mouse | LD50 | oral | 28915mg/kg (28915mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| mouse | LD50 | oral | 31gm/kg (31000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | oral | 34gm/kg (34000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | oral | 36gm/kg (36000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| mouse | LD50 | subcutaneous | 18gm/kg (18000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD | skin | > 1gm/kg (1000mg/kg) | Union Carbide Data Sheet. Vol. 9/25/1969, | |
| rabbit | LD50 | intravenous | 8gm/kg (8000mg/kg) | BLOOD: CHANGE IN CLOTTING FACTORS | Kriobiologiya i Kriomeditsina. Cryobiology and Cryomedicine. Vol. 4, Pg. 71, 1978. |
| rabbit | LD50 | oral | 14gm/kg (14000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rabbit | LD50 | oral | 17300mg/kg (17300mg/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | oral | 17300mg/kg (17300mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 19gm/kg (19000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rabbit | LD50 | oral | 26800mg/kg (26800mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 28900mg/kg (28900mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | oral | 76gm/kg (76000mg/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | oral | 76gm/kg (76000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rabbit | LD50 | skin | > 20mL/kg (20mL/kg) | International Journal of Toxicology. Vol. 18(Suppl, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-1112, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2202, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-96, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2203, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-937, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-939, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-935, | |
| rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Dow Chemical Company Reports. Vol. MSD-940, | |
| rat | LD | oral | > 4gm/kg (4000mg/kg) | Union Carbide Data Sheet. Vol. 9/25/1969, | |
| rat | LD50 | intraperitoneal | 6790mg/kg (6790mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 9gm/kg (9000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 9700mg/kg (9700mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intraperitoneal | 9708mg/kg (9708mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| rat | LD50 | intraperitoneal | 12600mg/kg (12600mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 14100mg/kg (14100mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intraperitoneal | 15390mg/kg (15390mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 15570mg/kg (15570mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intraperitoneal | 17gm/kg (17000mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| rat | LD50 | intraperitoneal | 17700mg/kg (17700mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | intravenous | 7130mg/kg (7130mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intravenous | 7312mg/kg (7312mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. | |
| rat | LD50 | intravenous | 7500mg/kg (7500mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982. | |
| rat | LD50 | intravenous | 13gm/kg (13000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 600mg/kg (600mg/kg) | Dow Chemical Company Reports. Vol. MSD-94, | |
| rat | LD50 | oral | 1054mg/kg (1054mg/kg) | Dow Chemical Company Reports. Vol. MSD-95, | |
| rat | LD50 | oral | > 4gm/kg (4000mg/kg) | Dow Chemical Company Reports. Vol. MSD-938, | |
| rat | LD50 | oral | 22gm/kg (22000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | 27500mg/kg (27500mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 28gm/kg (28000mg/kg) | Dow Chemical Company Reports. Vol. MSD-1112, | |
| rat | LD50 | oral | 30gm/kg (30000mg/kg) | Dow Chemical Company Reports. Vol. MSD-2203, | |
| rat | LD50 | oral | 30200mg/kg (30200mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950. | |
| rat | LD50 | oral | 31600mg/kg (31600mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | 31640mg/kg (31640mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 32gm/kg (32000mg/kg) | Dow Chemical Company Reports. Vol. MSD-937, | |
| rat | LD50 | oral | 44200mg/kg (44200mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 45gm/kg (45000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982. | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | > 50gm/kg (50000mg/kg) | Dow Chemical Company Reports. Vol. MSD-935, | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969. | |
| rat | LD50 | oral | > 50gm/kg (50000mg/kg) | Dow Chemical Company Reports. Vol. MSD-940, | |
| rat | LD50 | oral | 50gm/kg (50000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 51200mg/kg (51200mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | oral | 51310mg/kg (51310mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | subcutaneous | 16gm/kg (16000mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953. |
| rat | LD50 | unreported | 7800mg/kg (7800mg/kg) | United States Patent Document. Vol. #4767763, | |
| rat | LDLo | intravenous | 3mg/kg (3mg/kg) | Toxicology and Applied Pharmacology. Vol. 16, Pg. 442, 1970. | |
| rat | LDLo | intravenous | 22gm/kg (22000mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1087, 1973. |