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Substance Name: Polypropylene glycol
RN: 25322-69-4

Classification Codes

  • Biocompatible Materials
  • Skin / Eye Irritant
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)

Molecular Formulas

  • (C3-H6-O)mult-H2-O
  • (C3-H8-O2)mult-H2-O

Molecular Weight

  • 134.174
 
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Links to Resources

Names and Synonyms

Name of Substance

  • Polyoxypropylene (12)
  • Polyoxypropylene (15)
  • Polyoxypropylene (17)
  • Polyoxypropylene (20)
  • Polyoxypropylene (26)
  • Polyoxypropylene (30)
  • Polyoxypropylene (34)
  • Polyoxypropylene (9)
  • Polypropylene glycol
  • Polypropylene glycol (12)
  • Polypropylene glycol (15)
  • Polypropylene glycol (17)
  • Polypropylene glycol (20)
  • Polypropylene glycol (26)
  • Polypropylene glycol (30)
  • Polypropylene glycol (34)
  • Polypropylene glycol (9)
  • PPG-12
  • PPG-15
  • PPG-17
  • PPG-20
  • PPG-26
  • PPG-30
  • PPG-34
  • PPG-9

Synonyms

  • Actocol 51-530
  • Alkapal PPG-1200
  • Alkapal PPG-2000
  • Alkapal PPG-4000
  • alpha-Hydro-omega-hydroxypoly(oxy(methyl-1,2-ethanediyl))
  • alpha-Hydro-omega-hydroxypoly(oxypropylene)
  • Bloat guard
  • Caswell No. 680
  • Desmophen 360C
  • EC 500-039-8
  • Emkapyl
  • EPA Pesticide Chemical Code 068602
  • Glycols, polypropylene
  • HSDB 1266
  • Jeffox PPG 400
  • Laprol 2002
  • Lineartop E
  • Methyloxirane homopolymer
  • Napter E 8075
  • Niax 1025
  • Niax 11-27
  • Niax 61-582
  • Niax polyol ppg 4025
  • Niax ppg
  • Niax ppg 1025
  • Niax ppg 3025
  • Niax ppg 425
  • Oopg 1000
  • Oxirane, methyl-, homopolymer
  • P 400
  • P 4000 (polymer)
  • P.P.G 2025
  • P.P.G 3025
  • P.P.G 4025
  • P.P.G. 1000
  • P.P.G. 1025
  • P.P.G. 1200
  • P.P.G. 150
  • P.P.G. 1800
  • P.P.G. 400
  • P.P.G. 425
  • P.P.G. 750
  • Pluracol 1010
  • Pluracol 2010
  • Pluracol P 2010
  • Pluracol P 410
  • Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-hydroxy-
  • Poly(propylene oxide)
  • Polyglycol P 400
  • Polyglycol P-2000
  • Polyglycol P-4000
  • Polyglycol type P1200
  • Polyglycol type P2000
  • Polyglycol type P250
  • Polyglycol type P3000
  • Polyglycol type P400
  • Polyglycol type P750
  • Polymer 2
  • Polyoxypropylene
  • Polyoxypropylene glycol
  • Polypropylene glycol
  • Polypropylene glycol #1200
  • Polypropylene glycol #400
  • Polypropylene glycol #425
  • Polypropylene glycol #750
  • Polypropylene glycol 1025
  • Polypropylenglykol
  • Polypropylenglykol [Czech]
  • PPG
  • PPG-15
  • Propylan 8123
  • Propylene oxide homopolymer
  • Propylene oxide, propylene glycol polymer
  • SKF 18667
  • UNII-01SEY4236K
  • UNII-439253FIWJ
  • UNII-757HA1493R
  • UNII-9UO53X55W2
  • UNII-GK69D49CJ0
  • UNII-GS1E37J3P8
  • UNII-H5B6JCZ906
  • UNII-HW7M6WY97M
  • UNII-I29VQH0G0B
  • UNII-L63N6V755Z
  • UNII-OV0Q322E0U
  • UNII-SJG6V595V6
  • UNII-V86KZL3H2Z
  • Voranol P 1010
  • Voranol P 2000
  • Voranol P 4000

Systematic Names

  • Laprol 702
  • Poly(oxy(methyl-1,2-ethanediyl)), alpha-hydro-omega-hydroxy-
  • Polypropylene glycol
  • Polypropylene glycol #1000
  • Polypropylene glycol #1200
  • Polypropylene glycol #1800
  • Polypropylene glycol #400
  • Polypropylene glycol #425
  • Polypropylene glycol #750
  • Polypropylene glycol 1025
  • Polypropylene glycol 150
  • Polypropylene glycol 2000
  • Polypropylene glycol 2025
  • Polypropylene glycol 3025
  • Polypropylene glycol 4000
  • Polypropylene glycol 4025
  • Propane-1,2-diol, propoxylated

Superlist Names

  • Glycols, polypropylene
  • Polypropylene glycol
  • PPG

Registry Numbers

CAS Registry Number

  • 25322-69-4

FDA UNIIs

  • 01SEY4236K
  • 439253FIWJ
  • 757HA1493R
  • 9UO53X55W2
  • GK69D49CJ0
  • GS1E37J3P8
  • H5B6JCZ906
  • HW7M6WY97M
  • I29VQH0G0B
  • L63N6V755Z
  • OV0Q322E0U
  • SJG6V595V6
  • V86KZL3H2Z

Other Registry Numbers

  • 100357-60-6
  • 1014983-27-7
  • 1049785-16-1
  • 105844-84-6
  • 109489-48-7
  • 111146-16-8
  • 115450-63-0
  • 116958-46-4
  • 1169934-33-1
  • 117715-07-8
  • 117968-93-1
  • 118441-48-8
  • 119652-85-6
  • 120468-96-4
  • 1205544-87-1
  • 122392-88-5
  • 123687-98-9
  • 124448-74-4
  • 124631-70-5
  • 125147-71-9
  • 125386-95-0
  • 126906-04-5
  • 1269983-38-1
  • 130842-36-3
  • 131649-30-4
  • 133439-62-0
  • 134092-40-3
  • 134192-23-7
  • 135355-02-1
  • 1381802-76-1
  • 138704-46-8
  • 1419790-34-3
  • 143550-15-6
  • 143710-19-4
  • 145699-74-7
  • 146024-61-5
  • 150825-72-2
  • 152287-82-6
  • 161278-03-1
  • 171904-01-1
  • 174206-36-1
  • 174722-18-0
  • 176742-37-3
  • 187954-99-0
  • 205657-26-7
  • 2085678-39-1
  • 2133455-29-3
  • 250380-45-1
  • 252369-71-4
  • 27274-27-7
  • 27615-86-7
  • 28724-27-8
  • 29434-03-5
  • 310902-91-1
  • 34465-52-6
  • 372166-28-4
  • 37231-68-8
  • 380912-66-3
  • 380912-82-3
  • 39289-79-7
  • 39465-43-5
  • 51019-30-8
  • 51568-92-4
  • 51922-49-7
  • 52309-41-8
  • 53528-82-8
  • 53863-41-5
  • 54500-36-6
  • 56591-76-5
  • 57137-06-1
  • 61090-28-6
  • 63279-07-2
  • 64176-87-0
  • 64940-80-3
  • 660439-52-1
  • 66174-27-4
  • 66988-34-9
  • 68821-81-8
  • 69900-45-4
  • 70992-51-7
  • 74870-00-1
  • 75139-15-0
  • 777067-78-4
  • 78361-82-7
  • 80408-02-2
  • 80803-40-3
  • 81774-53-0
  • 81774-61-0
  • 824420-00-0
  • 82548-17-2
  • 84420-39-3
  • 84503-25-3
  • 84682-96-2
  • 85497-31-0
  • 865704-12-7
  • 87608-88-6
  • 879098-15-4
  • 87940-78-1
  • 88025-94-9
  • 89126-79-4
  • 9003-15-0
  • 907603-46-7
  • 9079-22-5
  • 9079-23-6
  • 9087-30-3
  • 91218-84-7
  • 913723-55-4
  • 92094-60-5
  • 942421-73-0
  • 94586-80-8
  • 956483-22-0
  • 97199-67-2
  • 98444-52-1
  • 98565-98-1
  • 98913-22-5
  • 99130-49-1

System Generated Number

  • 0025322694

Molecular Formulas

Molecular Formulas

  • (C3-H6-O)mult-H2-O
  • (C3-H8-O2)mult-H2-O

Molecular Formula Fragments

  • C3-H6-O
  • C3-H8-O2
  • COMPONENT
  • H2-O

Structure Descriptors

Smiles

O([C@@H](CO)C)C[C@@H](C)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
dog LDLo intravenous 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
guinea pig LD50 unreported 1200mg/kg (1200mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
mouse LD50 intraperitoneal 113mg/kg (113mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
mouse LD50 intraperitoneal 195mg/kg (195mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
mouse LD50 intraperitoneal 700mg/kg (700mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
mouse LD50 intraperitoneal 3600mg/kg (3600mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.
mouse LD50 unreported 4255mg/kg (4255mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 3/20/1973,
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 10/16/1973,
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 7/23/1970,
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 5/19/1960,
rabbit LD50 skin 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 3/27/1969,
rabbit LD50 skin 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 3/28/1969,
rabbit LD50 skin > 10gm/kg (10000mg/kg)   Dow Chemical Company Reports. Vol. MSD-95,
rabbit LD50 skin > 30gm/kg (30000mg/kg)   Dow Chemical Company Reports. Vol. MSD-395,
rat LD50 intraperitoneal 230uL/kg (0.23mL/kg)   Union Carbide Data Sheet. Vol. 7/23/1970,
rat LD50 intraperitoneal 460uL/kg (0.46mL/kg)   Union Carbide Data Sheet. Vol. 10/16/1973,
rat LD50 intraperitoneal 4470mg/kg (4470mg/kg) BEHAVIORAL: TREMOR AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951.
rat LD50 intravenous 100uL/kg (0.1mL/kg)   Union Carbide Data Sheet. Vol. 7/23/1970,
rat LD50 intravenous 200uL/kg (0.2mL/kg)   Union Carbide Data Sheet. Vol. 10/16/1973,
rat LD50 intravenous 710mg/kg (710mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 3, Pg. 448, 1951.
rat LD50 oral 35600uL/kg (35.6mL/kg)   Union Carbide Data Sheet. Vol. 3/27/1969,
rat LD50 oral 56600uL/kg (56.6mL/kg)   Union Carbide Data Sheet. Vol. 3/28/1969,
rat LD50 oral > 2gm/kg (2000mg/kg)   Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,
rat LD50 oral 2150mg/kg (2150mg/kg)   Union Carbide Data Sheet. Vol. 7/23/1970,
rat LD50 oral 2410mg/kg (2410mg/kg)   Union Carbide Data Sheet. Vol. 10/16/1973,
rat LD50 oral 3750mg/kg (3750mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(6), Pg. 73, 1981.
rat LD50 oral 4190mg/kg (4190mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986.
rat LD50 oral 7250mg/kg (7250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 1413, 1986.
rat LD50 oral 9760mg/kg (9760mg/kg)   Union Carbide Data Sheet. Vol. 5/19/1960,
rat LD50 oral 10334mg/kg (10334mg/kg)   Dow Chemical Company Reports. Vol. MSD-395,
rat LD50 oral 14800mg/kg (14800mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rat LD50 oral > 15gm/kg (15000mg/kg)   Dow Chemical Company Reports. Vol. MSD-508,