Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Emricasan [USAN:INN]
RN: 254750-02-2
UNII: P0GMS9N47Q
InChIKey: SCVHJVCATBPIHN-SJCJKPOMSA-N

Note

  • A caspase-3 inhibitor for treating liver disease.

Classification Codes

  • An Anti-Apoptotic Caspase Inhibitor
  • Prevention of Fibrosis and Inflammation in Chronic Liver Disease

Molecular Formula

  • C26-H27-F4-N3-O7

Molecular Weight

  • 569.5053
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Emricasan [USAN:INN]

Synonyms

  • (3S)-3-(N2-((2-Tert-butylphenyl)oxamoyl)-L-alaninamido)-4-oxo-5-(2,3,5,6- tetrafluorophenoxy)pentanoic acid
  • Emricasan
  • IDN 6556
  • PF 03491390
  • PF-03491390
  • UNII-P0GMS9N47Q

Systematic Name

  • L-Alaninamide, N-(2-(1,1-dimethylethyl)phenyl)-2-oxoglycyl-N-((1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl)-

Registry Numbers

CAS Registry Number

  • 254750-02-2

FDA UNII

  • P0GMS9N47Q

Other Registry Number

  • 624747-15-5

System Generated Number

  • 0254750022

Structure Descriptors

InChI

1S/C26H27F4N3O7/c1-12(31-24(38)25(39)32-16-8-6-5-7-13(16)26(2,3)4)23(37)33-17(10-19(35)36)18(34)11-40-22-20(29)14(27)9-15(28)21(22)30/h5-9,12,17H,10-11H2,1-4H3,(H,31,38)(H,32,39)(H,33,37)(H,35,36)/t12-,17-/m0/s1

InChIKey

SCVHJVCATBPIHN-SJCJKPOMSA-N

Smiles

C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F