Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Ibotenic acid
RN: 2552-55-8
UNII: 44AS82FRSI
InChIKey: IRJCBFDCFXCWGO-UHFFFAOYSA-N

Note

  • A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.

Molecular Formula

  • C5-H6-N2-O4

Molecular Weight

  • 158.1124
 

Classification Codes

  • Excitatory Amino Acid Agents
  • Excitatory Amino Acid Agonists
  • Neurotransmitter Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Ibotenic acid

MeSH Heading

  • Ibotenic acid

Synonyms

  • (RS)-Ibotenic acid
  • alpha-Amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid
  • DL-Ibotenic acid
  • Ibotenate
  • Ibotenic acid
  • NSC 204850
  • UNII-44AS82FRSI

Systematic Names

  • 4-Isoxazoline-5-acetic acid, alpha-amino-3-oxo-
  • 5-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-3-oxo-

Registry Numbers

CAS Registry Number

  • 2552-55-8

FDA UNII

  • 44AS82FRSI

Other Registry Number

  • 31758-99-3

System Generated Number

  • 0002552558

Structure Descriptors

InChI

1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)

InChIKey

IRJCBFDCFXCWGO-UHFFFAOYSA-N

Smiles

c1c(onc1O)C(C(=O)O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 15mg/kg (15mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 311, 1968.
mouse LD50 oral 38mg/kg (38mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 311, 1968.
rat LD50 intravenous 42mg/kg (42mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 311, 1968.
rat LD50 oral 129mg/kg (129mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 311, 1968.