Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Propidium iodide
RN: 25535-16-4
UNII: TP416O228T
InChIKey: XJMOSONTPMZWPB-UHFFFAOYSA-M

Note

  • Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Molecular Formula

  • C27-H34-N4.2I

Molecular Weight

  • 668.394
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Propidium iodide

Synonyms

  • 3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridinium diiodide
  • 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium iodide methiodide (6CI)
  • EINECS 247-081-0
  • NSC 169541
  • Propidium diiodide
  • Propidium iodide
  • UNII-TP416O228T

Systematic Names

  • 3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridinium diiodide
  • Phenanthridinium, 3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-, diiodide

Registry Numbers

CAS Registry Number

  • 25535-16-4

FDA UNII

  • TP416O228T

System Generated Number

  • 0025535164

Molecular Formulas

Molecular Formula

  • C27-H34-N4.2I

Molecular Formula Fragments

  • C27-H34-N4
  • COMPONENT
  • I

Structure Descriptors

InChI

1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1

InChIKey

XJMOSONTPMZWPB-UHFFFAOYSA-M

Smiles

Nc1cc2c(c3ccccc3)[n+](CCC[N+](CC)(CC)C)c3c(c2cc1)ccc(N)c3.[IH-].[IH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 16mg/kg (16mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 11, Pg. 334, 1956.