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Substance Name: Povidone-iodine [USP:BAN:JAN]
RN: 25655-41-8
UNII: 85H0HZU99M

Note

  • An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.

Molecular Formula

  • (C6-H9-N-O)x-.x-I2

Molecular Weight

  • 364.9431
 

Classification Codes

  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Anti-Infective, Topical
  • Drug / Therapeutic Agent
  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)

Names and Synonyms

Name of Substance

  • 1-Vinyl-2-pyrrolidinone polymer W/iodine
  • 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
  • Polyvinylpyrrolidone-iodine complex
  • Povidone-iodine
  • Povidone-iodine [USP:BAN:JAN]
  • PVP-Iodine

MeSH Heading

  • Povidone-iodine

Synonyms

  • 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine
  • 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine
  • 1-Vinyl-2-pyrrolidinone polymer, compound with iodine
  • 1-Vinyl-2-pyrrolidinone polymers, iodine complex
  • 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
  • Argentyne
  • Betadin
  • Betadine
  • Betadine (VAN)
  • Betaisodona
  • Braunol
  • Braunosan H
  • Bridine
  • CCRIS 9290
  • Disadine D.P.
  • Disphex
  • E-Z Prep
  • E-Z Prep 220
  • E-Z Scrub
  • E-Z Scrub 201
  • E-Z Scrub 241
  • Efo-dine
  • HSDB 6831
  • Inadine
  • Iodinated poly(vinylpyrrolidone)
  • Iodine-poly(vinylpyrrolidinone)
  • Iodine-polyvinylpyrrolidone complex
  • Iodopoly(vinyl pyrrolidinone)
  • Isobetadyne
  • Isodine
  • NSC 26245
  • Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex
  • Poly(vinylpyrrolidinone) iodide
  • Poly(vinylpyrrolidinone)-iodine complex
  • Poly(vinylpyrrolidone) - iodine complex
  • Poly(vinylpyrrolidone)-iodine adduct
  • Polyvinylpyrrolidone compound with iodine
  • Polyvinylpyrrolidone-iodine complex
  • Povadyne
  • Povidone iodine
  • Povidone-iodine
  • Povidone-lodine
  • Proviodine
  • PVP iodine
  • Pvp-1
  • PVP-I
  • PVP-Iodine
  • PVP-Iodine, 30-06
  • Traumasept
  • Ultradine
  • UNII-85H0HZU99M
  • Videne

Systematic Names

  • 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
  • 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with iodine (8CI)
  • Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex

Superlist Name

  • Polyvinylpyrrolidone - iodine complex

Registry Numbers

CAS Registry Number

  • 25655-41-8

FDA UNII

  • 85H0HZU99M

Other Registry Numbers

  • 113813-78-8
  • 1202865-55-1
  • 1216458-36-4
  • 1219590-00-7
  • 1246654-78-3
  • 129947-86-0
  • 130095-86-2
  • 138115-12-5
  • 180749-13-7
  • 26856-09-7
  • 30849-75-3
  • 36703-90-9
  • 9006-37-5
  • 94555-99-4

System Generated Number

  • 0025655418

Molecular Formulas

Molecular Formula

  • (C6-H9-N-O)x-.x-I2

Molecular Formula Fragments

  • C6-H9-N-O
  • COMPONENT
  • I

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo skin 3400mg/kg/24H (3400mg/kg) BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
JAMA, Journal of the American Medical Association. Vol. 240, Pg. 249, 1978.
mouse LD50 intravenous 480mg/kg (480mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.
mouse LD50 oral 8100mg/kg (8100mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.
mouse LD50 subcutaneous 4100mg/kg (4100mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.
rat LD50 intravenous 640mg/kg (640mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.
rat LD50 oral > 8gm/kg (8000mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.
rat LD50 subcutaneous 3450mg/kg (3450mg/kg)   Drugs in Japan Vol. 6, Pg. 788, 1982.